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RXFP1 antibody (AA 68-162)

RXFP1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3E3 unconjugated
Catalog No. ABIN566200
  • Target See all RXFP1 Antibodies
    RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))
    Binding Specificity
    • 14
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 68-162
    Reactivity
    • 47
    • 9
    • 8
    • 2
    • 1
    Human
    Host
    • 44
    • 3
    Mouse
    Clonality
    • 46
    • 1
    Monoclonal
    Conjugate
    • 21
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RXFP1 antibody is un-conjugated
    Application
    • 30
    • 20
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant LGR7.
    Sequence
    WSMQFDKYFA SYYKMTSQYP FEAETPECLV GSVPVQCLCQ GLELDCDETN LRAVPSVSSN VTAMSLQWNL IRKLPPDCFK NYHDLQKLYL QNNKI
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    LGR7 (NP_067647, 68 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    3E3
    Isotype
    IgG2a
    Top Product
    Discover our top product RXFP1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Jelinic, Leo, Post Uiterweer, Sandow, Gooi, Wlodek, Conrad, Parkington, Tare, Parry: "Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 1, pp. 275-87, (2014) (PubMed).

    Ferlin, Menegazzo, Gianesello, Selice, Foresta: "Effect of relaxin on human sperm functions." in: Journal of andrology, Vol. 33, Issue 3, pp. 474-82, (2012) (PubMed).

    Soh, Tiwari, Mahendroo, Conrad, Parry: "Relaxin regulates hyaluronan synthesis and aquaporins in the cervix of late pregnant mice." in: Endocrinology, Vol. 153, Issue 12, pp. 6054-64, (2012) (PubMed).

    Vandevoort, Mtango, Latham, Stewart: "Primate preimplantation embryo is a target for relaxin during early pregnancy." in: Fertility and sterility, Vol. 96, Issue 1, pp. 203-7, (2011) (PubMed).

    Ferlin, Pepe, Facciolli, Gianesello, Foresta: "Relaxin stimulates osteoclast differentiation and activation." in: Bone, Vol. 46, Issue 2, pp. 504-13, (2010) (PubMed).

    Vodstrcil, Shynlova, Verlander, Wlodek, Parry: "Decreased expression of the rat myometrial relaxin receptor (RXFP1) in late pregnancy is partially mediated by the presence of the conceptus." in: Biology of reproduction, Vol. 83, Issue 5, pp. 818-24, (2010) (PubMed).

    Feng, Agoulnik, Truong, Li, Creighton, Kaftanovskaya, Pereira, Han, Lopez-Berestein, Klonisch, Ittmann, Sood, Agoulnik: "Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis." in: Endocrine-related cancer, Vol. 17, Issue 4, pp. 1021-33, (2010) (PubMed).

    Kern, Bryant-Greenwood: "Characterization of relaxin receptor (RXFP1) desensitization and internalization in primary human decidual cells and RXFP1-transfected HEK293 cells." in: Endocrinology, Vol. 150, Issue 5, pp. 2419-28, (2009) (PubMed).

  • Target
    RXFP1 (Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1))
    Alternative Name
    RXFP1 (RXFP1 Products)
    Synonyms
    LGR7 antibody, RXFPR1 antibody, Gm1018 antibody, Lgr7 antibody, RXFP2 antibody, relaxin/insulin like family peptide receptor 1 antibody, relaxin/insulin-like family peptide receptor 1 antibody, RXFP1 antibody, rxfp1 antibody, Rxfp1 antibody
    Background
    Full Gene Name: relaxin/insulin-like family peptide receptor 1
    Synonyms: LGR7,LGR7.1,LGR7.10,LGR7.2,MGC138347,MGC142177,RXFPR1
    Gene ID
    59350
    NCBI Accession
    NM_021634
    Pathways
    Myometrial Relaxation and Contraction
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