RAB7B antibody (AA 100-199)

Catalog No. ABIN567027

Product Details anti-RAB7B Antibody

Target: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Binding Specificity: AA 100-199

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAB7B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Purpose: Mouse monoclonal antibody raised against a partial recombinant RAB7B.

Sequence: DIWRGDVLAK IVPMEQSYPM VLLGNKIDLA DRKVPQEVAQ GWCREKDIPY FEVSAKNDIN VVQAFEMLAS RALSRYQSIL ENHLTESIKL SPDQSRSRCC

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RAB7B (NP_796377, 100 a.a. ~ 199 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3B3

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RAB7B antibody (ABIN567027)

Margiotta, Progida, Bakke, Bucci: "Rab7a regulates cell migration through Rac1 and vimentin." in: Biochimica et biophysica acta, Vol. 1864, Issue 2, pp. 367-381, (2016) (PubMed).

Borg, Bakke, Progida: "A novel interaction between Rab7b and actomyosin reveals a dual role in intracellular transport and cell migration." in: Journal of cell science, Vol. 127, Issue 22, pp. 4927-39, (2014) (PubMed).

Zlatic, Tornieri, LHernault, Faundez: "Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells." in: Molecular biology of the cell, Vol. 22, Issue 10, pp. 1699-715, (2011) (PubMed).

Higashi, Iseki, Minegishi, Togo, Kabuta, Wada: "GIGYF2 is present in endosomal compartments in the mammalian brains and enhances IGF-1-induced ERK1/2 activation." in: Journal of neurochemistry, Vol. 115, Issue 2, pp. 423-37, (2010) (PubMed).

Zhu, Salazar, Zlatic, Fiza, Doucette, Heilman, Levey, Faundez, Lhernault: "SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery." in: Molecular biology of the cell, Vol. 20, Issue 4, pp. 1223-40, (2009) (PubMed).

Higashi, Moore, Yamamoto, Minegishi, Sato, Togo, Katsuse, Uchikado, Furukawa, Hino, Kosaka, Emson, Wada, Dawson, Dawson, Arai, Iseki: "Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease." in: Journal of neuropathology and experimental neurology, Vol. 68, Issue 9, pp. 994-1005, (2009) (PubMed).

Target Details for RAB7B

Target: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Alternative Name: RAB7B (RAB7B Products)

Synonyms: RGD1562617 antibody, RAB7B antibody, RAB7 antibody, Rab7b antibody, Rab7b, member RAS oncogene family antibody, rab7B protein antibody, RAB7B, member RAS oncogene family antibody, RAB7B, member RAS oncogene family S homeolog antibody, Rab7b antibody, rab7B antibody, RAB7B antibody, rab7b.S antibody, rab7b antibody

Background: Full Gene Name: RAB7B, member RAS oncogene family
Synonyms: MGC16212,MGC9726,RAB7

Gene ID: 338382

NCBI Accession: NM_177403