HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (AA 61-83) antibody

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AA 61-83
(27), (11), (8), (7), (7), (5), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
(333), (8), (5), (1), (1)
(217), (98), (21), (6), (3), (1)
Clonality (Clone)
Monoclonal ()
(40), (34), (31), (20), (13), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1)
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(165), (149), (136), (57), (54), (49), (41), (33), (30), (24), (11), (7), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 9 references available
Quantity 0.1 mg
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Clone 4H84
Isotype IgG1
Specificity The antibody 4H84 recognizes HLA-G molecule (39 kDa).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity Chromatography on Protein A
Alternative Name HLA Class I alpha G / HLA-G (HLAG Antibody Abstract)
Background HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblast cells.Synonyms: HLA class I histocompatibility antigen, HLA-6.0, HLAG, MHC class I antigen G
Gene ID 3135
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (AA 61-83) antibody (ABIN567601) anti-HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (AA 61-83) antibody
Immunohistochemistry (IHC) image for anti-HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (AA 61-83) antibody (ABIN567601) anti-HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG) (AA 61-83) antibody (Image 2)
Background publications Barrier, Kendall, Sharpe-Timms et al.: "Characterization of human leukocyte antigen-G (HLA-G) expression in endometrial adenocarcinoma." in: Gynecologic oncology, Vol. 103, Issue 1, pp. 25-30, 2006 (PubMed).

Juch, Blaschitz, Daxböck et al.: "A novel sandwich ELISA for alpha1 domain based detection of soluble HLA-G heavy chains." in: Journal of immunological methods, Vol. 307, Issue 1-2, pp. 96-106, 2005 (PubMed).

Gonen-Gross, Achdout, Arnon et al.: "The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 8, pp. 4866-74, 2005 (PubMed).

Poláková, Kuba, Russ: "The 4H84 monoclonal antibody detecting beta2m free nonclassical HLA-G molecules also binds to free heavy chains of classical HLA class I antigens present on activated lymphocytes." in: Human immunology, Vol. 65, Issue 2, pp. 157-62, 2004 (PubMed).

Poláková, Krcová, Kuba et al.: "Analysis of HLA-G expression in malignant hematopoetic cells from leukemia patients." in: Leukemia research, Vol. 27, Issue 7, pp. 643-8, 2003 (PubMed).

Menier, Saez, Horejsi et al.: "Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules." in: Human immunology, Vol. 64, Issue 3, pp. 315-26, 2003 (PubMed).

Blaschitz, Hutter, Dohr: "HLA Class I protein expression in the human placenta." in: Early pregnancy (Online), Vol. 5, Issue 1, pp. 67-9, 2001 (PubMed).

Urosevic, Kurrer, Kamarashev et al.: "Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 production." in: The American journal of pathology, Vol. 159, Issue 3, pp. 817-24, 2001 (PubMed).

Paul, Rouas-Freiss, Khalil-Daher et al.: "HLA-G expression in melanoma: a way for tumor cells to escape from immunosurveillance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 8, pp. 4510-5, 1998 (PubMed).

Catalog No. ABIN567601
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