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TUBB2B antibody (Tubulin, beta 2B)

Details for Product anti-TUBB2B Antibody No. ABIN567612, Supplier: Log in to see
Antigen
Alternatives
anti-Human TUBB2B antibody for Western Blotting
Reactivity
Human, Mouse (Murine)
60
5
3
Host
Mouse
31
29
Clonality (Clone)
Monoclonal ()
Conjugate
This TUBB2B antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
44
33
23
21
8
6
3
Supplier
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Clone AT5B3
Isotype IgG2a
Specificity The antibody recognizes Human and Mouse TUBB2B. Other species not tested.
Purification Protein-G affinity chromatography
Alternative Name TUBB2B (TUBB2B Antibody Abstract)
Background The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. Multiple beta Tubulin isoforms have been characterized and are expressed in mammalian tissues. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2b is mainly expressed in developing neurons with a dominant expression during the critical steps of corticogenesis. Also, TUBB2B is a new critical gene involved in neuronal migration. It is present in the nuclei and nucleoplasm, Defects in this gene are a cause of asymmetric polymicrogyria.Synonyms: RP11-506K6.1, Tubulin beta-2B chain, beta II Tubulin B, beta-Tubulin
Gene ID 347733
Pathways Microtubule Dynamics
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Immunofluorescence (IF) image for anti-TUBB2B antibody (Tubulin, beta 2B) (ABIN567612) anti-Tubulin, beta 2B (TUBB2B) antibody
Immunohistochemistry (IHC) image for anti-TUBB2B antibody (Tubulin, beta 2B) (ABIN567612) anti-Tubulin, beta 2B (TUBB2B) antibody (Image 2)
Western Blotting (WB) image for anti-TUBB2B antibody (Tubulin, beta 2B) (ABIN567612) anti-Tubulin, beta 2B (TUBB2B) antibody (Image 3)
Immunofluorescence (IF) image for anti-TUBB2B antibody (Tubulin, beta 2B) (ABIN567612) anti-Tubulin, beta 2B (TUBB2B) antibody (Image 4)
Background publications Jaglin, Poirier, Saillour et al.: "Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria." in: Nature genetics, Vol. 41, Issue 6, pp. 746-52, 2010 (PubMed).

Bouwmeester, Bauch, Ruffner et al.: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ..." in: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, 2004 (PubMed).