Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody

Details for Product No. ABIN567850
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Antigen
Reactivity
Human
(393), (187), (68), (41), (30), (20), (11), (5), (2), (1)
Host
Mouse
(295), (163), (81), (4), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(59), (46), (31), (18), (10), (5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(299), (201), (125), (118), (103), (76), (63), (56), (41), (20), (20), (10), (5), (4), (2), (1), (1), (1), (1)
Pubmed 7 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
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Catalog No. ABIN567850
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Clone CB31
Specificity Recognizes CD31 / PECAM1
Purification Protein G Chromatography
Alternative Name CD31 / PECAM1
Background CD31 antibody (clone CB31) reacts with a type I transmembrane glycoprotein (130 kDa) called CD31. CD31 is a surface protein expressed by endothelial cells, monocytes, platelets, granulocytes, and lymphocyte subsets. Reports indicate that CD31 interacts with CD38 and is involved in cellular interactions resulting in cell migration, wound healing and angiogenesis.
Alternate names: EndoCAM, GPIIA', PECAM-1, Platelet endothelial cell adhesion molecule
Gene ID 9606
UniProt P16284
Research Area CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.05% BSA and 0.05% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for 6 months (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
Background publications Fawcett, Buckley, Holness et al.: "Mapping the homotypic binding sites in CD31 and the role of CD31 adhesion in the formation of interendothelial cell contacts." in: The Journal of cell biology, Vol. 128, Issue 6, pp. 1229-41, 1995 (PubMed).

Vaporciyan, DeLisser, Yan et al.: "Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo." in: Science (New York, N.Y.), Vol. 262, Issue 5139, pp. 1580-2, 1993 (PubMed).

DeLisser, Newman, Albelda: "Platelet endothelial cell adhesion molecule (CD31)." in: Current topics in microbiology and immunology, Vol. 184, pp. 37-45, 1994 (PubMed).

Muller, Weigl, Deng et al.: "PECAM-1 is required for transendothelial migration of leukocytes." in: The Journal of experimental medicine, Vol. 178, Issue 2, pp. 449-60, 1993 (PubMed).

Newman: "The biology of PECAM-1." in: The Journal of clinical investigation, Vol. 99, Issue 1, pp. 3-8, 1997 (PubMed).

Woodfin, Voisin, Nourshargh: "PECAM-1: a multi-functional molecule in inflammation and vascular biology." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 27, Issue 12, pp. 2514-23, 2007 (PubMed).

Wu, Madri: "Insights into monocyte-driven osteoclastogenesis and its link with hematopoiesis: regulatory roles of PECAM-1 (CD31) and SHP-1." in: Critical reviews in immunology, Vol. 30, Issue 5, pp. 423-33, 2010 (PubMed).

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