anti-GAPDH antibody (Glyceraldehyde-3-Phosphate Dehydrogenase) (AA 279-290)

Details for Product anti-GAPDH Antibody No. ABIN567894
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Antigen
Epitope
AA 279-290
(92), (50), (19), (16), (10), (9), (9), (8), (8), (7), (7), (5), (5), (5), (4), (4), (4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Monkey, Mouse (Murine), Pig (Porcine)
(513), (210), (180), (104), (54), (40), (34), (33), (18), (18), (17), (17), (17), (16), (14), (10), (9), (8), (8), (7), (7), (7), (6), (6), (6), (6), (5), (5), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Mouse
(304), (227), (56), (28), (22)
Clonality (Clone)
Monoclonal ()
Conjugate
This GAPDH antibody is un-conjugated
(38), (34), (15), (6), (6), (6), (6), (6), (6), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(583), (280), (155), (121), (73), (67), (36), (28), (24), (14), (12), (9), (7), (5), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1)
Pubmed 4 references available
Quantity 25 μg
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Availability Discontinued
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Immunogen Amino acids 279-290 of Glyceraldehyde 3-Phosphate Dehydrogenase protein
Sequence HQVVSSDFNS DT
Clone IMG13H12
Isotype IgG1
Specificity Recognizes GAPDH.
Purification Protein G Chromatography
Alternative Name GAPDH (GAPDH Antibody Abstract)
Background Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export. GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer’s and Huntington’s disease. GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
Alternate names: CDABP0047, GAPD, Glyceraldehyde-3-Phosphate Dehydrogenase
Gene ID 2597
NCBI Accession NP_002037
UniProt P04406
Research Area Cancer, Metabolism, Alzheimer's Disease, Enzymes
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.05% BSA and 0.05% Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 279-290) antibody anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 279-290) antibody
anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 279-290) antibody (2) anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 279-290) antibody (Image 2)
Background publications Ellis, Earnhardt, Hayes et al.: "Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats." in: Journal of neurochemistry, Vol. 88, Issue 3, pp. 689-97, 2004 (PubMed).

Fortun, Dunn, Joy et al.: "Emerging role for autophagy in the removal of aggresomes in Schwann cells." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 23, Issue 33, pp. 10672-80, 2003 (PubMed).

Burke, Enghild, Martin et al.: "Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH." in: Nature medicine, Vol. 2, Issue 3, pp. 347-50, 1996 (PubMed).

Stroud, Levery, Mårtensson et al.: "Human tumor-associated Le(a)-Le(x) hybrid carbohydrate antigen IV3(Gal beta 1-->3[Fuc alpha 1-->4]GlcNAc)III3FucnLc4 defined by monoclonal antibody 43-9F: enzymatic synthesis, structural characterization, and comparative reactivity with various antibodies" in: Biochemistry, Vol. 33, Issue 35, pp. 10672-80, 1994 (PubMed).

Validation Images
Catalog No. ABIN567894
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