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Interleukin 25 (IL25) antibody

Details for Product No. ABIN567924
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Antigen
Synonyms IL17E, Il17e, IL-17e, RGD1561632, IL25
Reactivity
Human
(47), (15), (6), (3), (3), (3)
Host
Mouse
(27), (22), (6), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(6), (3), (2), (2), (2), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(51), (35), (16), (15), (8), (6), (6), (1), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
Catalog No. ABIN567924
456.50 $
Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Full-length IL-17E/IL-25 recombinant protein
Clone 8B1
Isotype IgG1
Specificity This antibody reacts to Interleukin-17E (IL-17E/IL-25).
Purification Protein G Chromatography
Alternative Name Interleukin-25 / IL25
Background As a member of the IL-17 family, IL-17E/IL-25 has been identified as a pro-inflammatory cytokine which is produced by Th17 effector cells thus enabling the TH17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis (1-3). IL-17E appears to stimulate IL-8 production and itself appears to be activated through IL-23, IL-6, and TGF-ß (1). The murine homolog of IL-17E has been termed IL-25 (3). Studies of IL-17E expression and activation through NF-kB taken together with IL-17 production and Th17 polarization through TLR ligand activation further closely tie the IL-17 and Th17 family together with the TLR signaling network initiating and controlling immune responses (4-7).
Alternate names: IL-17E, IL-25, IL17E, Interleukin-17E
Gene ID 64806
NCBI Accession NP_073626.1
UniProt Q9H293
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer PBS containing 0.05% BSA and 0.05% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Interleukin 25 (IL25) antibody anti-Interleukin 25 (IL25) antibody
anti-Interleukin 25 (IL25) antibody (2) anti-Interleukin 25 (IL25) antibody (Image 2)
Background publications Lee, Ho, Maruoka et al.: "IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1." in: The Journal of biological chemistry, Vol. 276, Issue 2, pp. 1660-4, 2001 (PubMed).

Ghilardi, Ouyang: "Targeting the development and effector functions of TH17 cells." in: Seminars in immunology, Vol. 19, Issue 6, pp. 383-93, 2008 (PubMed).

Hosts (27), (22), (6), (3)
Reactivities (47), (15), (6), (3), (3), (3)
Applications (51), (35), (16), (15), (8), (6), (6), (1), (1), (1), (1), (1)
Conjugates (6), (3), (2), (2), (2), (1), (1)
Epitopes (8), (7), (4), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN567924
456.50 $
Plus shipping costs $45.00
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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