ZCCHC11 antibody (C-Term)

Catalog No. ABIN568022

Product Details anti-ZCCHC11 Antibody

Target: ZCCHC11 (Zinc Finger, CCHC Domain Containing 11 (ZCCHC11))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This ZCCHC11 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: RERCPHPPRG NVSE

Specificity: This antibody is expected to recognize all 3 reported isoforms.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog) and Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the C Terminus of the protein according to NP_001009881.1, NP_056084.1 and NP_001009882.1. Genename: ZCCHC11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ZCCHC11

Target: ZCCHC11 (Zinc Finger, CCHC Domain Containing 11 (ZCCHC11))

Alternative Name: ZCCHC11 (ZCCHC11 Products)

Synonyms: PAPD3 antibody, TUT4 antibody, ZCCHC11 antibody, DKFZp459G145 antibody, 6030404K05Rik antibody, 9230115F04Rik antibody, PPAPD3 antibody, mKIAA0191 antibody, wu:fc06h08 antibody, wu:fy37g11 antibody, papd3 antibody, zinc finger CCHC-type containing 11 antibody, zinc finger, CCHC domain containing 11 antibody, zinc finger CCHC domain containing 11 antibody, ZCCHC11 antibody, Zcchc11 antibody, zcchc11 antibody

Background: ZCH11 is known to direct cytokine expression by uridylating cytokine-targeting miRNAs. ZCH11 is a ribonucleotidyltransferase with a preference for uridine and is essential for maintaining the poly(A) tail length and stability of transcripts for interleukin-6 (IL-6), plus other specific cytokines.Synonyms: KIAA0191, Zinc finger CCHC domain-containing protein 11

Gene ID: 23318

NCBI Accession: NP_001009881

UniProt: Q5TAX3

Pathways: Stem Cell Maintenance