Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Ceruloplasmin antibody

CP Reactivity: Human WB, IP, IHC (p), IF, EIA, RIA, ID, DB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN568138
  • Target See all Ceruloplasmin (CP) Antibodies
    Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))
    Reactivity
    • 54
    • 11
    • 9
    Human
    Host
    • 47
    • 8
    • 6
    • 4
    • 1
    Rabbit
    Clonality
    • 57
    • 7
    Polyclonal
    Conjugate
    • 40
    • 10
    • 6
    • 4
    • 2
    • 2
    • 2
    This Ceruloplasmin antibody is un-conjugated
    Application
    • 41
    • 30
    • 26
    • 14
    • 13
    • 10
    • 9
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Radioimmunoassay (RIA), Immunodiffusion (ID), Dot Blot (DB)
    Specificity
    The antibody recognizes Ceruloplasmin from Human serum. The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: Immunoelectrophoresis, Cross-Immunoelectrophoresis, single Radial Immunodiffusion (Ouchterlony), Block titration, ELISA, Immunoblotting and Enzyme Inhibition. Cross-reactivities against enzymes of other sources may occur but have not been determined.
    Purification
    Ammonium Sulphate Precipitation and Ion Exchange Chromatography
    Immunogen
    Ceruloplasmin isolated and purified from Human serum. Freund's complete adjuvant is used in the first step of the immunization procedure.
    Isotype
    IgG
    Top Product
    Discover our top product CP Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore by adding 1.0 mL of sterile distilled water. Prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2) and preferably use the same day.
    Concentration
    10.0 mg/mL
    Buffer
    PBS, pH 7.2 without preservatives and foreign proteins
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))
    Alternative Name
    Ceruloplasmin (CP Products)
    Synonyms
    CP-2 antibody, fi23f10 antibody, wu:fi23f10 antibody, D3Ertd555e antibody, CERP antibody, CP antibody, ceruloplasmin antibody, CP antibody, cp antibody, Cp antibody, LOC100533122 antibody
    Background
    Caeruloplasmin is a copper binding plasma glycoprotein consisting of a single polypeptide chain. It has a molecular weight of 132 kDa and occurs in plasma at a concentration of 150-500 mg/L. Although the physiological functions of Caeruloplasmin are not fully understood it is implicated in a number of possible functions. 95 % of plasma copper is bound to Caeruloplasmin, implying some involvement in copper transport. Caeruloplasmin has been described as both an oxidant and an antioxidant, its exact role or roles in this respect are not clear. Plasma levels of Caeruloplasmin are elevated after inflammation and trauma and it is therefore classified as an acute phase protein. The measurement of Caeruloplasmin in plasma is useful in the diagnosis of Wilson's disease, where levels are greatly reduced. Caeruloplasmin is extremely labile in plasma and rapidly degrades to 115 kDa and 19 kDa fragments. The age of plasma samples should therefore be taken into account when interpreting immunological analysis of caeruloplasmin.Synonyms: CP, Ferroxidase
    Gene ID
    1356
    NCBI Accession
    NP_000087
    UniProt
    P00450
    Pathways
    Transition Metal Ion Homeostasis
You are here:
Support