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CIRBP antibody (Internal Region)
CIRBP
Reactivity: Human, Mouse, Rat, Dog, Cow
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-CIRBP Antibody
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Target
See all CIRBP Antibodies
CIRBP
(Cold Inducible RNA Binding Protein (CIRBP))
Binding Specificity
All epitopes for CIRBP antibodies
AA 81-91, Internal Region
Reactivity
All reactivities for CIRBP antibodies
Human, Mouse, Rat, Dog, Cow
Host
All hosts for CIRBP antibodies
Goat
Clonality
All clonalities for CIRBP antibodies
Polyclonal
Conjugate
All conjugates for CIRBP antibodies
This CIRBP antibody is un-conjugated
Application
All applications for CIRBP antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
C-QAGKSSDNRS R
Specificity
Recognizes CIRBP (aa 81-91).
Cross-Reactivity (Details)
Species reactivity (expected):Human, Dog, Cow. Species reactivity (tested):Mouse, Rat.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_001271.1. Genename: CIRBP
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Discover our top product CIRBP Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for CIRBP
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Target
CIRBP
(Cold Inducible RNA Binding Protein (CIRBP))
Alternative Name
CIRBP (CIRBP Products )
Synonyms
CIRP antibody, Cirp antibody, R74941 antibody, Xcirp antibody, cirbp antibody, cirbp-a antibody, cirbp2 antibody, cirp antibody, cirp1 antibody, cirp2 antibody, xcirp2 antibody, XCIRP antibody, XCIRP-1 antibody, cirbp-b antibody, cirp-1 antibody, APBP-1 antibody, zgc:136559 antibody, CIRBP antibody, A18 hnRNP antibody, cold inducible RNA binding protein antibody, cold-inducible RNA-binding protein antibody, cold inducible RNA binding protein S homeolog antibody, cold inducible RNA binding protein L homeolog antibody, cold inducible RNA binding protein b antibody, CIRBP antibody, EDI_107320 antibody, Cirbp antibody, cirbp.S antibody, cirbp.L antibody, cirbp antibody, cirbpb antibody
Background
CIRBP, also named as A18HNRNP and CIRP, is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP is also involved in cap-independent translation upon moderate cold-shock. It acts as a translational activator. CIRBP is a suppressive rather stimulatory effect on proliferation. It acts as a translational repressor. CIRBP is an immortalized gene in murine primary cells. CIRBP promotes assembly of stress granules (SGs), when overexpressed. It is a potential proto-oncogenic proteins upon overexpression. Suppression of CIRBP increased the apoptotic cell population of neural stem cells at moderate low temperature.Synonyms: A18HNRNP, CIRP, Cold-inducible RNA-binding protein, Glycine-rich RNA-binding protein CIRP
Gene ID
1153
NCBI Accession
NP_001271
UniProt
Q14011
Pathways
Ribonucleoprotein Complex Subunit Organization
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