PSMB4 antibody (Internal Region)

Catalog No. ABIN568707

Product Details anti-PSMB4 Antibody

Target: PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))

Binding Specificity: AA 230-239, Internal Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This PSMB4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-NRFQIATVTE

Specificity: Recognizes PSMB4 (aa 230-239).

Cross-Reactivity (Details): Species reactivity (expected):Canine (Dog), Bovine, Rabbit.
Species reactivity (tested):Human, Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence (230-239) from the internal region of the protein sequence according to NP_002787.2. Genename: PSMB4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PSMB4

Target: PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))

Alternative Name: PSMB4 / PROS26 (PSMB4 Products)

Synonyms: An18g06680 antibody, PSMB4 antibody, Pros-27 antibody, HN3 antibody, HsN3 antibody, PROS-26 antibody, PROS26 antibody, im:6909492 antibody, zgc:110330 antibody, proteasome subunit beta type-4 antibody, proteasome subunit beta 4 antibody, proteasome (prosome, macropain) subunit, beta type 4 antibody, proteasome subunit beta 4 L homeolog antibody, ANI_1_890164 antibody, PSMB4 antibody, psmb4 antibody, Psmb4 antibody, psmb4.L antibody

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.Synonyms: HsBPROS26, HsN3, Macropain beta chain, Multicatalytic endopeptidase complex beta chain, PROS-26, Proteasome beta chain, Proteasome chain 3, Proteasome subunit beta type-4

Gene ID: 5692

NCBI Accession: NP_002787

UniProt: P28070

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA