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NOD1 antibody (C-Term)
NOD1
Reactivity: Human
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-NOD1 Antibody
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Target
See all NOD1 Antibodies
NOD1
(Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
Binding Specificity
All epitopes for NOD1 antibodies
C-Term
Reactivity
All reactivities for NOD1 antibodies
Human
Host
All hosts for NOD1 antibodies
Goat
Clonality
All clonalities for NOD1 antibodies
Polyclonal
Conjugate
All conjugates for NOD1 antibodies
This NOD1 antibody is un-conjugated
Application
All applications for NOD1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
EAKVYEDEKR IICF
Specificity
Recognizes NOD1 / CARD4 (C-term).
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Immunogen
Peptide with sequence from the C Terminus of the protein sequence according to NP_006083.1. Genename: NOD1
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Discover our top product NOD1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for NOD1
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Target
NOD1
(Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
Alternative Name
CARD4 / NOD1 (NOD1 Products )
Synonyms
CARD4 antibody, CLR7.1 antibody, NLRC1 antibody, C230079P11 antibody, Card4 antibody, F830007N14Rik antibody, Nlrc1 antibody, RGD1562269 antibody, nucleotide binding oligomerization domain containing 1 antibody, nucleotide-binding oligomerization domain containing 1 antibody, NOD1 antibody, Nod1 antibody
Background
CARD4 is a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.Synonyms: Caspase recruitment domain-containing protein 4, Nucleotide-binding oligomerization domain-containing protein 1
Gene ID
10392
NCBI Accession
NP_006083
UniProt
Q9Y239
Pathways
Activation of Innate immune Response , Positive Regulation of Endopeptidase Activity , Toll-Like Receptors Cascades , Inflammasome
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