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Fuzzy Homolog (Drosophila) (FUZ) (AA 338-355) antibody

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AA 338-355
(5), (4), (1), (1), (1)
Human, Monkey, Mouse (Murine), Rat (Rattus)
(11), (1), (1), (1)
Western Blotting (WB)
(10), (4), (1), (1), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mg
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Immunogen A synthetic peptide corresponding to amino acids 338-355 (TSTHFPPEPGPPEKTEDE) of human FUZ .Remarks: 100% homologous in human and chimpanzee 81% homologous in mouse and rat 77% homologous in dog
Specificity This anitbody will detect a number of isoforms of the FUZ protein ranging from 269 amino acids to 418 amino acids. Species Reactivity: Tested: Chimpanzee, Human, Mouse, Rat. Expected from sequence similarity: Canine.
Purification Protein G chromatography
Alternative Name Protein fuzzy homolog (FUZ Antibody Abstract)
Background FUZ is the human homolog of Drosophila fy protein and belongs to the fuzzy family. The fy gene of Drosophila encodes a novel four-pass transmembrane protein that plays two roles in the development of hairs on the Drosophila wing. The first is to specify the correct orientation of the hair by restricting its initiation to the distal vertex of the cell. The second role is to permit the development of just a single cell hair by maintaining the integrity of the F-actin and microtubule arrays that are required for hair development. In humans, the protein is involved in cytoskeleton function and cell polarity in epithelial cells. The human fuz gene is localized on chromosome 19q13.33.
Alternate names: FUZ
Gene ID 70300
NCBI Accession NP_081652
UniProt Q3UYI6
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer PBS containing 0.05% BSA and 0.05% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Catalog No. ABIN569018

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