Msh Homeobox 1 (MSX1) (AA 50-100) antibody

Details for Product No. ABIN569091
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Antigen
Epitope
AA 50-100
(9), (8), (7), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
(60), (20), (18), (14), (14), (3)
Host
Rabbit
(38), (13), (9), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(40), (29), (11), (10), (10), (10), (9), (5), (5), (3), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
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Catalog No. ABIN569091
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Immunogen A portion of amino acids 50-100 of human HOX7 .Remarks: 100% homologous in human, chimpanzee, monkey, rat and mouse 94% homologous in cow 92% homologous in chicken 88% homologous in opossum
Specificity This antibody reacts to HOX7/MSX-1. Species Reactivity: Tested: Chimpanzee, Human, New World monkey, Mouse, Rat. Expected from sequence similarity: Cow, Xenopus, Chicken, Opossum.
Purification Protein G chromatography
Alternative Name MSX1
Background HOX7 is a 297 amino acid novel member of homeodomain family of DNA binding domain family (meta HOX) that functions as a DNA-associated transcription factor. It has a helix- turn-helix and DNA binding domain. It plays an important role in inhibiting MYOD1 expression and is involved in epithelial-mesenchymal signaling in many organs, playing a role in limb-pattern formation. It acts as a potential repressor in cell cycle progression and as a RNA polymerase 2 transcription factor, involved in skeletal development. Northern blot analysis detects highest expression of HOX7 in heart along with other tissues like prostate and highly in dental mesenchyme during critical bud stage, placenta, etc.
Alternate names: HOX7, Homeobox protein Hox-7, Homeobox protein MSX-1, Hox-7, MSX-1, Msh homeobox 1-like protein
Gene ID 4487
NCBI Accession NP_002439
UniProt P28360
Research Area Organogenesis, Transcription Factors, Neural Stem Cell marker
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer PBS containing 0.2% gelatin and 0.05% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Hewitt, Clark, Ivens et al.: "Structure and sequence of the human homeobox gene HOX7." in: Genomics, Vol. 11, Issue 3, pp. 670-8, 1992 (PubMed).

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

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