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Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG) (AA 2-13) antibody

Details for Product No. ABIN569108
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Antigen
Epitope
AA 2-13
(24), (23), (19), (15), (12), (9), (9), (7), (6), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(214), (48), (46), (25), (14), (2), (2)
Host
Rabbit
(181), (35), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (3), (3), (3)
Application
Western Blotting (WB)
(161), (105), (50), (39), (37), (23), (22), (20), (2), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
Catalog No. ABIN569108
434.50 $
Plus shipping costs $45.00
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  • +1 404 474 4654
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Immunogen Peptide corresponding to amino acids 2-13 [NRHLWKSQLCEM] of the IKKg protein.
Specificity This antibody reacts to IKKg/IKK3/NEMO.
Purification Protein G chromatography
Alternative Name NEMO / IKBKG
Background Pro-inflammatory cytokines activate the transcription factor NF-kappaB by stimulating the activity of a protein kinase that phosphorylates IkappaB, an inhibitor of NF-kappaB, at sites that trigger its ubiquitination and degradation. A large, cytokine-responsive IkappaB kinase (IKK) complex contains 2 subunits, IKK-alpha and IKK-beta, which are protein kinases whose function is needed for NF-kappaB activation by pro-inflammatory stimuli. IKK is composed of similar amounts of IKK-alpha, IKK-beta, which are differentially processed forms of a third subunit, IKK-gamma. IKK-gamma interacts preferentially with IKK- beta and is required for the activation of the IKK complex.
Alternate names: FIP-3, FIP3, I-kappa-B kinase subunit gamma, IKK-gamma, IKKAP1, IKKG, IkB kinase subunit gamma, IkB kinase-associated protein 1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, NF-kappa-B essential modifier, NF-kappa-B essential modulator
Gene ID 8517
NCBI Accession NP_001093326.2
UniProt Q9Y6K9
Restrictions For Research Use only
Format Liquid
Concentration 1,0 mg/mL
Buffer PBS containing 0.02% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Scheidereit: "Signal transduction. Docking IkappaB kinases." in: Nature, Vol. 395, Issue 6699, pp. 225-6, 1998 (PubMed).

Rothwarf, Zandi, Natoli et al.: "IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex." in: Nature, Vol. 395, Issue 6699, pp. 297-300, 1998 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN569108
434.50 $
Plus shipping costs $45.00
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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