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TP53 Apoptosis Effector (PERP) (AA 37-50), (Extracellular Loop) antibody

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Extracellular Loop, AA 37-50
(45), (15), (6), (4), (2), (2), (2), (1), (1)
(68), (6), (4), (4), (2), (2), (1)
(53), (16)
(3), (3), (3), (3), (3), (3), (1)
Western Blotting (WB)
(61), (36), (20), (8), (8), (3), (2), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
Immunogen Peptide corresponding to amino acids 37-50 of human PERP .Remarks: This region is in the first extracellular loop of the protein.
Specificity This antibody detects PERP (37-50). Species Reactivity: Tested: Human
Purification Purified
Alternative Name PERP (PERP Antibody Abstract)
Background The p53 tumor suppressor activates either cell cycle arrest or apoptosis in response to cellular stress. A novel gene, PERP, is expressed in a p53-dependent manner and at high levels in apoptotic cells compared with G(1)-arrested cells. PERP induction is linked to p53-dependent apoptosis and is directly activated by p53. These data suggest that PERP is a novel effector of p53-dependent apoptosis.
Alternate names: KCP-1, KCP1, KRTCAP1, Keratinocyte-associated protein 1, P53-induced protein PIGPC1, PERP, PIGPC1, THW, Transmembrane protein THW, p53 apoptosis effector related to PMP-22
Gene ID 64065
NCBI Accession NP_071404
UniProt Q96FX8
Research Area Signaling, Extracellular Matrix, Apoptosis/Necrosis
Restrictions For Research Use only
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Attardi, Reczek, Cosmas et al.: "PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family." in: Genes & development, Vol. 14, Issue 6, pp. 704-18, 2000 (PubMed).

Catalog No. ABIN569296

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