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Details for Product No. ABIN569296

TP53 Apoptosis Effector (PERP) (Extracellular Loop), (AA 37-50) antibody

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Synonyms THW, KCP1, PIGPC1, KRTCAP1, 1110017A08Rik, dJ496H19.1, RP3-496H19.1, PERP, PERPL, kcp1, krtcap1, pigpc1, thw, fk24g11, wu:fk24g11, LOC100221212
»Alternatives Extracellular Loop, AA 37-50
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN569296
Quantity 0.1 mg
368.50 $   Plus shipping costs $45.00
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Availability Discontinued
Immunogen Peptide corresponding to amino acids 37-50 of human PERP .Remarks: This region is in the first extracellular loop of the protein.
Specificity This antibody detects PERP (37-50). Species Reactivity: Tested: Human
Purification Purified
Alternative Name PERP
Background The p53 tumor suppressor activates either cell cycle arrest or apoptosis in response to cellular stress. A novel gene, PERP, is expressed in a p53-dependent manner and at high levels in apoptotic cells compared with G(1)-arrested cells. PERP induction is linked to p53-dependent apoptosis and is directly activated by p53. These data suggest that PERP is a novel effector of p53-dependent apoptosis.
Alternate names: KCP-1, KCP1, KRTCAP1, Keratinocyte-associated protein 1, P53-induced protein PIGPC1, PERP, PIGPC1, THW, Transmembrane protein THW, p53 apoptosis effector related to PMP-22
Gene ID 64065
NCBI Accession NP_071404.2
UniProt Q96FX8
Research Area Signaling, Extracellular Matrix, Apoptosis/Necrosis
Restrictions For Research Use only
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Attardi, Reczek, Cosmas et al.: "PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family." in: Genes & development, Vol. 14, Issue 6, pp. 704-18, 2000 (PubMed).

Alternatives for antigen "TP53 Apoptosis Effector (PERP)", type "Antibodies"
Hosts (44), (6)
Reactivities (47), (14), (13), (12), (11), (11)
Applications (39), (15), (10), (9), (9), (4), (4), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (17), (3), (2), (2), (1), (1), (1)