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TP53 Apoptosis Effector (PERP) (Extracellular Loop), (AA 37-50) antibody

Details for Product No. ABIN569296
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Antigen
Epitope
Extracellular Loop, AA 37-50
(22), (7), (3), (2), (2), (1), (1)
Reactivity
Human
(52), (14), (13), (12), (11), (11)
Host
Rabbit
(49), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(43), (20), (11), (10), (9), (8), (4), (1), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
Catalog No. ABIN569296
368.50 $
Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide corresponding to amino acids 37-50 of human PERP .Remarks: This region is in the first extracellular loop of the protein.
Specificity This antibody detects PERP (37-50). Species Reactivity: Tested: Human
Purification Purified
Alternative Name PERP
Background The p53 tumor suppressor activates either cell cycle arrest or apoptosis in response to cellular stress. A novel gene, PERP, is expressed in a p53-dependent manner and at high levels in apoptotic cells compared with G(1)-arrested cells. PERP induction is linked to p53-dependent apoptosis and is directly activated by p53. These data suggest that PERP is a novel effector of p53-dependent apoptosis.
Alternate names: KCP-1, KCP1, KRTCAP1, Keratinocyte-associated protein 1, P53-induced protein PIGPC1, PERP, PIGPC1, THW, Transmembrane protein THW, p53 apoptosis effector related to PMP-22
Gene ID 64065
NCBI Accession NP_071404.2
UniProt Q96FX8
Research Area Signaling, Extracellular Matrix, Apoptosis/Necrosis
Restrictions For Research Use only
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Attardi, Reczek, Cosmas et al.: "PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family." in: Genes & development, Vol. 14, Issue 6, pp. 704-18, 2000 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN569296
368.50 $
Plus shipping costs $45.00
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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