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Details for Product No. ABIN569307

PR Domain Containing 5 (PRDM5) (AA 100-200) antibody

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Antigen
Synonyms BCS2, PFM2, AI197291, 4432417F03Rik, 6530401I24Rik, E130112L17Rik, PRDM5
Epitope
»Alternatives AA 100-200
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN569307
Quantity 0.1 mg
Price
445.50 $   Plus shipping costs $45.00
Shipping to
Availability Discontinued
Immunogen Amino acids 100-200 of human PRDM5 protein
Specificity This antibody detects PRDM5 / PFM2. Species Reactivity: Tested: Human Expected from sequence similarity: Dog
Purification Protein G chromatography
Alternative Name PRDM5 / PFM2
Background PRDM5, a novel member of PR domain protein family, contains a PR-domain at the –NH2 terminus followed by 16 zinc finger motifs. It is found to have a role in cell differentiation and tumorigenesis. Reports suggest PRDM5 causes G2/M arrest and apoptosis upon infection of tumor cells and has been found to be silenced in breast, ovarian and lung cancers, suggesting a potential clinical significance.
Alternate names: PR domain zinc finger protein 5, PR domain-containing protein 5
Gene ID 11107
NCBI Accession NP_061169.2
UniProt Q9NQX1
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2% gelatin and 0.05% sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Jiang, Huang: "The yin-yang of PR-domain family genes in tumorigenesis." in: Histology and histopathology, Vol. 15, Issue 1, pp. 109-17, 2000 (PubMed).

Xiao, Wilson, Gamblin: "SET domains and histone methylation." in: Current opinion in structural biology, Vol. 13, Issue 6, pp. 699-705, 2003 (PubMed).

Deng, Huang: "PRDM5 is silenced in human cancers and has growth suppressive activities." in: Oncogene, Vol. 23, Issue 28, pp. 4903-10, 2004 (PubMed).

Alternatives for antigen "PR Domain Containing 5 (PRDM5)", type "Antibodies"
Hosts (18)
Reactivities (18), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Applications (15), (6), (3), (1), (1), (1)
Epitopes (6), (3), (2), (1), (1), (1), (1)
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