PR Domain Containing 5 (PRDM5) (AA 100-200) antibody

Details for Product No. ABIN569307
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Antigen
Epitope
AA 100-200
(11), (7), (3), (2), (1), (1), (1), (1)
Reactivity
Human
(20), (2), (2), (2), (2), (2), (1)
Host
Rabbit
(20)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(18), (8), (4), (1), (1)
Pubmed 3 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Discontinued
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Catalog No. ABIN569307
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Immunogen Amino acids 100-200 of human PRDM5 protein
Specificity This antibody detects PRDM5 / PFM2. Species Reactivity: Tested: Human Expected from sequence similarity: Dog
Purification Protein G chromatography
Alternative Name PRDM5 / PFM2
Background PRDM5, a novel member of PR domain protein family, contains a PR-domain at the –NH2 terminus followed by 16 zinc finger motifs. It is found to have a role in cell differentiation and tumorigenesis. Reports suggest PRDM5 causes G2/M arrest and apoptosis upon infection of tumor cells and has been found to be silenced in breast, ovarian and lung cancers, suggesting a potential clinical significance.
Alternate names: PR domain zinc finger protein 5, PR domain-containing protein 5
Gene ID 11107
NCBI Accession NP_061169
UniProt Q9NQX1
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2% gelatin and 0.05% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Jiang, Huang: "The yin-yang of PR-domain family genes in tumorigenesis." in: Histology and histopathology, Vol. 15, Issue 1, pp. 109-17, 2000 (PubMed).

Xiao, Wilson, Gamblin: "SET domains and histone methylation." in: Current opinion in structural biology, Vol. 13, Issue 6, pp. 699-705, 2003 (PubMed).

Deng, Huang: "PRDM5 is silenced in human cancers and has growth suppressive activities." in: Oncogene, Vol. 23, Issue 28, pp. 4903-10, 2004 (PubMed).

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