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PR Domain Containing 5 (PRDM5) (AA 100-200) antibody

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AA 100-200
(21), (15), (7), (2), (1), (1), (1), (1)
(39), (5), (5), (2), (2), (2), (1)
(38), (1)
(2), (2), (2), (2), (2), (2)
Western Blotting (WB)
(34), (17), (5), (5), (1), (1), (1)
Pubmed 3 references available
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Quantity 0.1 mg
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Immunogen Amino acids 100-200 of human PRDM5 protein
Specificity This antibody detects PRDM5 / PFM2. Species Reactivity: Tested: Human Expected from sequence similarity: Dog
Purification Protein G chromatography
Alternative Name PRDM5 / PFM2 (PRDM5 Antibody Abstract)
Background PRDM5, a novel member of PR domain protein family, contains a PR-domain at the –NH2 terminus followed by 16 zinc finger motifs. It is found to have a role in cell differentiation and tumorigenesis. Reports suggest PRDM5 causes G2/M arrest and apoptosis upon infection of tumor cells and has been found to be silenced in breast, ovarian and lung cancers, suggesting a potential clinical significance.
Alternate names: PR domain zinc finger protein 5, PR domain-containing protein 5
Gene ID 11107
NCBI Accession NP_061169
UniProt Q9NQX1
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.2% gelatin and 0.05% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Deng, Huang: "PRDM5 is silenced in human cancers and has growth suppressive activities." in: Oncogene, Vol. 23, Issue 28, pp. 4903-10, 2004 (PubMed).

Xiao, Wilson, Gamblin: "SET domains and histone methylation." in: Current opinion in structural biology, Vol. 13, Issue 6, pp. 699-705, 2003 (PubMed).

Jiang, Huang: "The yin-yang of PR-domain family genes in tumorigenesis." in: Histology and histopathology, Vol. 15, Issue 1, pp. 109-17, 2000 (PubMed).

Catalog No. ABIN569307

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