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Patched 2 antibody (PTCH2) (AA 226-235)

Details for Product anti-PTCH2 Antibody No. ABIN569318, Supplier: Login to see New
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AA 226-235
(8), (6), (4), (4), (2), (1), (1), (1), (1), (1)
Human, Mouse (Murine)
(27), (6), (4), (3), (2), (1), (1), (1)
(29), (5)
Western Blotting (WB)
(26), (12), (3), (2), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
Immunogen Peptide corresponding to amino acids 226-235 of human PTCH2
Specificity This antibody detects PTCH2. Species Reactivity: Tested: Mouse, human
Purification Protein G purified
Alternative Name PTCH2 (PTCH2 Antibody Abstract)
Background Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.
Alternate names: PTC2, Protein patched homolog 2, patched 2
Gene ID 8643
NCBI Accession NP_001159764
UniProt Q9Y6C5
Research Area Cancer, Cell Cycle, Transcription Factors
Pathways Hedgehog Signaling
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 0.02% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Smyth, Narang, Evans et al.: "Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32." in: Human molecular genetics, Vol. 8, Issue 2, pp. 291-7, 1999 (PubMed).

Catalog No. ABIN569318

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