Reproductive Homeobox 13 (RHOX13) (AA 1-50), (N-Term) antibody

Details for Product No. ABIN569366
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Synonyms 1700123J19Rik
AA 1-50, N-Term
Mouse (Murine)
Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN569366
Quantity 0.1 mg
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Immunogen Amino acids 1-50 of Rhox-13 .Remarks: The amino acid sequence used as immunogen is 100% homologous in mouse and 59% homologous in rat.
Specificity This antibody detects Rhox-13. Species Reactivity: Tested: Mouse Expected from sequence similarity: Rat
Purification Antigen affinity chromatography
Alternative Name Rhox13
Background The Rhox-13 protein is a reproductive homeobox protein found on the X chromosome. This transcription factor belongs to the homeobox gene family whose expression organizes programs of development. Reproductive homeobox genes regulate development of reproductive tissues including the testis, ovary, and placenta. Most of the Rhox genes are expressed in Sertoli cells, the nurse cells in direct contact with developing male germ cells. This suggests that they regulate the expression of somatic-cell gene products critical for germ cell development. Transcripts of this protein are found in the testis and ovary as early as 13.5 days post coitum. Transcription ceases in the ovary three days post partum, but continues in the testis through adulthood.
Alternate names: Reproductive homeobox 13, Rhox-13
NCBI Accession 10090
UniProt A2A3Z1
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS containing 0.05% BSA and 0.05% sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Expiry Date 12 months
Background publications Maclean, Chen, Wayne et al.: "Rhox: a new homeobox gene cluster." in: Cell, Vol. 120, Issue 3, pp. 369-82, 2005 (PubMed).

Geyer, Eddy: "Identification and characterization of Rhox13, a novel X-linked mouse homeobox gene." in: Gene, Vol. 423, Issue 2, pp. 194-200, 2008 (PubMed).

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