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TNF Receptor-Associated Factor 1 (TRAF1) (AA 51-69) antibody

Details for Product No. ABIN569503
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Antigen
Epitope
AA 51-69
(7), (7), (6), (4), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine)
(47), (24), (17), (13), (13), (1)
Host
Rabbit
(39), (7), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(39), (22), (13), (10), (7), (4), (3), (1), (1), (1)
Pubmed 2 references available
Quantity 50 µL
Shipping to United States (Change)
Availability Discontinued
Catalog No. ABIN569503
423.50 $
Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide corresponding to amino acids 51-69 of mouse TRAF1
Sequence CRADNLHPVSPGSPLTQEK
Specificity This antibody recognizes TRAF1, Mouse TRAF1 is a 409 amino acid protein. Species Reactivity: Tested: Mouse
Purification Serum
Alternative Name TRAF1 / EBI6
Background The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.
Alternate names: Epstein-Barr virus-induced protein 6, TNF receptor-associated factor 1
NCBI Accession 10090
UniProt P39428
Restrictions For Research Use only
Format Liquid
Buffer 0.05% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Expiry Date 12 months
Background publications Chung, Park, Ye et al.: "All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction." in: Journal of cell science, Vol. 115, Issue Pt 4, pp. 679-88, 2002 (PubMed).

Rao, Ghosh, Douillard et al.: "An essential role of ubiquitination in Cbl-mediated negative regulation of the Src-family kinase Fyn." in: Signal transduction, Vol. 2, Issue 1-2, pp. 29-39, 2010 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN569503
423.50 $
Plus shipping costs $45.00
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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