TNF Receptor-Associated Factor 4 (TRAF4) (AA 1-17), (N-Term) antibody

Details for Product No. ABIN569509
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

 
Antigen
Synonyms CART1, MLN62, RNF83, A530032M13Rik, msp2, traf4, cart1, mln62, rnf83, traf-4
Epitope
AA 1-17, N-Term
(9), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(53), (27), (27), (14), (13), (2), (1)
Host
Rabbit
(44), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(39), (23), (11), (10), (6), (4), (3), (3), (2), (2), (1)
Pubmed 2 references available
Catalog no. ABIN569509
Quantity 50 µL
Price
423.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Discontinued
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide corresponding to amino acids 1-17 of human TRAF4
Sequence MPGFDYKFLEKPKRRLL
Specificity This antibody detects TRAF4 / RNF83. Species Reactivity: Tested: Cow, Human, Mouse, Rat, Zebrafish
Purification Serum
Alternative Name TRAF4 / RNF83
Background The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.
Alternate names: CART1, Cysteine-rich domain associated with RING and Traf domains protein 1, MLN62, Malignant 62, RING finger protein 83, TNF receptor-associated factor 4
Gene ID 9618
NCBI Accession NP_004286.2
UniProt Q9BUZ4
Restrictions For Research Use only
Format Liquid
Buffer 0.05% sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Expiry Date 12 months
Background publications Chung, Park, Ye et al.: "All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction." in: Journal of cell science, Vol. 115, Issue Pt 4, pp. 679-88, 2002 (PubMed).

Rao, Ghosh, Douillard et al.: "An essential role of ubiquitination in Cbl-mediated negative regulation of the Src-family kinase Fyn." in: Signal transduction, Vol. 2, Issue 1-2, pp. 29-39, 2010 (PubMed).

Hosts (44), (8)
Reactivities (53), (27), (27), (14), (13), (2), (1)
Applications (39), (23), (11), (10), (6), (4), (3), (3), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
back to top