POU4F3 antibody (Internal Region)

Catalog No. ABIN569584

Product Details anti-POU4F3 Antibody

Target: POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This POU4F3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-EAAYREKNSK PE

Specificity: Recognizes POU4F3. This antibody is expected not to cross-react to the similar POU4F1 and POU4F2.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog).
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002691.1. Genename: POU4F3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for POU4F3

Target: POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))

Alternative Name: POU4F3 (POU4F3 Products)

Synonyms: POU4F3 antibody, BRN-3 antibody, BRN3 antibody, BRN3C antibody, DFNA15 antibody, BRN-3.1 antibody, brn-3c antibody, brn3.1 antibody, brn3c antibody, Brn3.1 antibody, Brn3c antibody, ddl antibody, dreidel antibody, POU class 4 homeobox 3 antibody, POU domain, class 4, transcription factor 3 antibody, POU4F3 antibody, Pou4f3 antibody, pou4f3 antibody

Background: POU4F3 (Pou domain, class 4, transcription factor 3) may play a role in determining or maintaining the identities of a small subset of visual system neurons since POU4F3 is required for retinal ganglion cell differentiation. It is also necessary for maturation and survival of hair cells in the inner ear. Defects in POU4F3 are the cause of non-syndromic sensorineural deafness autosomal dominant type 15 (DFNA15).Synonyms: BRN3C, Brain-3C, Brain-specific homeobox/POU domain protein 3C, Brn-3C, POU domain class 4 transcription factor 3

Gene ID: 5459

NCBI Accession: NP_002691

UniProt: Q15319

Pathways: Sensory Perception of Sound