CFTR (N-Term) antibody
| Antigen |
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Epitope
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N-Term
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| Clonality |
Polyclonal |
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Host
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Application
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 Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Immunofluorescence (IF) (26), Flow Cytometry (FACS) (18), Western Blotting (WB) (13), Immunoprecipitation (IP) (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), ELISA (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1)
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| Catalog no. |
ABIN571833 |
| Quantity |
100 µl |
| Price |
413.33 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Alternative name
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CFTR (n-terminal region)
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Format
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Lyophilized
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Description
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FUNCTION: Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Defects in CFTR are the cause of congenital bilateral absence of the vas deferens (CBAVD). CBAVD is an important cause of sterility in men and could represent an incomplete form of cystic fibrosis, as the majority of men suffering from cystic fibrosis lack the vas deferens. Subcellular location: Membrane, Multi-pass membrane protein. Tissue specificity: Found on the surface of the epithelial cells that line the lungs and other organs. Also known as: Cystic fibrosistransmembrane conductance regulator, Channel conductance-controlling ATPase, cAMP-dependent chloride channel, ATP-binding cassette transporter sub-family C member 7.
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Application Notes
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IHC, WB (confirmed by recombinant protein). A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
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Purity
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whole serum
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Storage
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Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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Restrictions
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For Research Use only
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Alternatives for antigen "CFTR", type "Antibodies"
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Hosts
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Rabbit (23), Mouse (14)
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Reactivities
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Human (35), Rat (Rattus) (21), Mouse (Murine) (20), Cow (Bovine) (18), Dog (Canine) (18), Pig (Porcine) (18), Chicken (16), Horse (Equine) (16), Rabbit (16), Sheep (Ovine) (16)
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Applications
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Immunofluorescence (IF) (26), Flow Cytometry (FACS) (18), Western Blotting (WB) (13), Immunoprecipitation (IP) (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), ELISA (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunohistochemistry (IHC) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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