TRPC1 antibody (AA 722-733)

Catalog No. ABIN574045

Product Details anti-TRPC1 Antibody

Target: TRPC1 (Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1))

Binding Specificity: AA 722-733

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Monkey, Pig, Rabbit, Chicken

Host: Goat

Clonality: Polyclonal

Conjugate: This TRPC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human TRPC1.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard, Pufferfish (100%) Bat, Trout, Seabass, Stickleback, Zebrafish (92%) Xenopus (83%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide NLKQKRDENYQK from internal region of human TRPC1 (NP_003295.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard, Pufferfish (100%), Bat, Trout, Seabass, Stickleback, Zebrafish (92%), Xenopus (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TRPC1

Target: TRPC1 (Transient Receptor Potential Cation Channel, Subfamily C, Member 1 (TRPC1))

Alternative Name: TRPC1 (TRPC1 Products)

Synonyms: HTRP-1 antibody, TRP1 antibody, Trrp1 antibody, xtrpc1 antibody, Mtrp1 antibody, Trp1 antibody, Trpc1 antibody, transient receptor potential cation channel subfamily C member 1 antibody, transient receptor potential cation channel, subfamily C, member 1 antibody, transient receptor potential cation channel, subfamily C, member 1 L homeolog antibody, TRPC1 antibody, Trpc1 antibody, trpc1.L antibody, trpc1 antibody

Background: Name/Gene ID: TRPC1
Subfamily: Calcium channel - TRP
Family: Ion Channel

Synonyms: TRPC1, HTRP-1, TRP1, TRP-1, Trrp1, Transient receptor protein 1

Gene ID: 7220

NCBI Accession: NP_003295

UniProt: P48995