TRPC4 antibody (AA 953-965)

Catalog No. ABIN574386

Product Details anti-TRPC4 Antibody

Target: TRPC4 (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 (TRPC4))

Binding Specificity: AA 953-965

Reactivity: Human, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This TRPC4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human TRPC4. This antibody is expected to recognise all six reported isoforms (NP_057263.1, NP_003297.1, NP_001129427.1, NP_001129429.1, NP_001129428.1, NP_001129430.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Dog (100%) Gibbon, Mouse, Rat, Hamster, Bovine (92%) Marmoset, Elephant, Panda, Pig (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KHAKEEDSSIDYD from an internal region (near C-terminus) of human TRPC4 (NP_057263.1, NP_003297.1, NP_001129427.1, NP_001129429.1, NP_001129428.1, NP_001129430.1). Percent identity by BLAST analysis: Human, Gorilla, Dog (100%), Gibbon, Mouse, Rat, Hamster, Bovine (92%), Marmoset, Elephant, Panda, Pig (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (4.75 μg/mL), Peptide-ELISA (1:32000), WB (0.3 - 1 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Approx. 110kD band observed in Rat Brain lysates (calculated MW of 112kD according to Human NP_057263.1 and to Rat NP_536321.1). Recommended concentration: 0.3-1 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TRPC4

Target: TRPC4 (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 (TRPC4))

Alternative Name: TRPC4 (TRPC4 Products)

Synonyms: TRPC5 antibody, TRPC4 antibody, HTRP-4 antibody, HTRP4 antibody, TRP4 antibody, CCE1 antibody, STRPC4 antibody, Trp4 antibody, Trrp4 antibody, transient receptor potential cation channel subfamily C member 4 antibody, short transient receptor potential channel 4 antibody, transient receptor potential cation channel, subfamily C, member 4 antibody, TRPC4 antibody, LOC100538928 antibody, trpc4 antibody, Trpc4 antibody

Background: Name/Gene ID: TRPC4
Subfamily: Calcium channel - TRP
Family: Ion Channel

Synonyms: TRPC4, CCE1, HTRP-4, HTRP4, TRP4, STRPC4, Trrp4, Trp-related protein 4

Gene ID: 7223

NCBI Accession: NP_057263, NP_003297, NP_001129427, NP_001129429, NP_001129428, NP_001129430

UniProt: Q9UBN4