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CD11b antibody (PE)

ITGAM Reactivity: Human, Baboon, Rhesus Monkey, Cynomolgus FACS, IHC, IP, IHC (fro) Host: Mouse Monoclonal PE
Catalog No. ABIN576541
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 257
    • 168
    • 62
    • 33
    • 17
    • 16
    • 15
    • 14
    • 11
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    Human, Baboon, Rhesus Monkey, Cynomolgus
    Host
    • 136
    • 104
    • 103
    • 4
    • 1
    • 1
    Mouse
    Clonality
    • 249
    • 96
    • 1
    Monoclonal
    Conjugate
    • 119
    • 37
    • 29
    • 25
    • 20
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is conjugated to PE
    Application
    • 259
    • 83
    • 74
    • 71
    • 59
    • 39
    • 36
    • 27
    • 22
    • 20
    • 13
    • 13
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Recognizes the human CD11b cell surface antigen, also known as the alphaM integrin. CD11b forms a heterodimer with CD18 and is expressed by circulating monocytes, granulocytes and also by dendritic reticulum cells in lymphoid tissue. Expression is increased on activated granulocytes. The CD11b molecule is the receptor for C3bi, fibrinogen and clotting factor X.
    No Cross-Reactivity
    Cat (Feline)
    Purification
    Protein G purified
    Immunogen
    Rheumatoid synovial cells and human monocytes.

    Type of Immunogen: Cells
    Isotype
    IgG1
    Top Product
    Discover our top product ITGAM Primary Antibody
  • Application Notes
    Approved: Flo (1:1), IHC, IHC-Fr, IP

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 100 μL of whole blood or 10^6 cells in 100 μL. Method sheets are available on request.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Distilled Water.
    Concentration
    Lot specific
    Buffer
    Lyophilized, PBS, 0.09 % sodium azide, 1 % BSA.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    ITGAM / CD11b (ITGAM Products)
    Synonyms
    CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
    Background
    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
    Gene ID
    3684
    UniProt
    P11215
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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