CD11b antibody (PE)
-
- Target See all CD11b (ITGAM) Antibodies
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
-
Reactivity
- Human, Baboon, Rhesus Monkey, Cynomolgus
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This CD11b antibody is conjugated to PE
-
Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Recognizes the human CD11b cell surface antigen, also known as the alphaM integrin. CD11b forms a heterodimer with CD18 and is expressed by circulating monocytes, granulocytes and also by dendritic reticulum cells in lymphoid tissue. Expression is increased on activated granulocytes. The CD11b molecule is the receptor for C3bi, fibrinogen and clotting factor X.
- No Cross-Reactivity
- Cat (Feline)
- Purification
- Protein G purified
- Immunogen
-
Rheumatoid synovial cells and human monocytes.
Type of Immunogen: Cells - Isotype
- IgG1
- Top Product
- Discover our top product ITGAM Primary Antibody
-
-
- Application Notes
-
Approved: Flo (1:1), IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 100 μL of whole blood or 10^6 cells in 100 μL. Method sheets are available on request. - Comment
-
Target Species of Antibody: Human
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Distilled Water.
- Concentration
- Lot specific
- Buffer
- Lyophilized, PBS, 0.09 % sodium azide, 1 % BSA.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Alternative Name
- ITGAM / CD11b (ITGAM Products)
- Synonyms
- CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
- Background
-
Name/Gene ID: ITGAM
Family: Integrin
Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain - Gene ID
- 3684
- UniProt
- P11215
- Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
-