KLRK1 antibody

Catalog No. ABIN601719

Product Details anti-KLRK1 Antibody

Target: KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLRK1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Specificity: Recognizes human CD314. Reported to inhibit T cell recognition of MICA (1,6).

Purification: Protein G purified

Endotoxin Level: Low Endotoxin

Immunogen: NKL cells.

Clone: 1D11

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:50 - 1:200), Func, IHC, IHC-Fr, IP

Usage: Suitable for use in Flow Cytometry, Functional Assays, Immunohistochemistry (frozen), and Immunoprecipitation. Flow Cytometry: 1:50-1:200, 10 μL labels 10^6 cells in 100 μL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4. No preservatives added

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.

Target Details for KLRK1

Target: KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))

Alternative Name: KLRK1 / CD314 / NKG2D (KLRK1 Products)

Synonyms: KLRK1 antibody, NKG2D antibody, CD314 antibody, D12S2489E antibody, KLR antibody, NKG2-D antibody, D6H12S2489E antibody, Nkg2d antibody, Nkrp2 antibody, killer cell lectin like receptor K1 antibody, killer cell lectin-like receptor subfamily K, member 1 antibody, NKG2D protein antibody, KLRK1 antibody, Klrk1 antibody, NKG2D antibody

Background: Name/Gene ID: KLRK1

Synonyms: KLRK1, D12S2489E, CD314 antigen, KLR, NK cell receptor D, NKG2D, NKG2-D, NKG2-D-activating NK receptor, CD314

Gene ID: 22914

UniProt: P26718

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process