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CD40 antibody (CD40 Molecule, TNF Receptor Superfamily Member 5) (PE)

Details for Product anti-CD40 Antibody No. ABIN610077, Supplier: Log in to see
Antigen
  • AI326936
  • Bp50
  • GP39
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TRAP
  • Tnfrsf5
  • p50
  • CDW40
  • TNFRSF5
  • TNFSF5
  • 2310042E05Rik
  • C130077D06Rik
  • C87049
  • DCTN-50
  • GMP23-48K
  • RBP50
  • CD40 antigen
  • CD40 molecule, TNF receptor superfamily member 5
  • dynactin 2
  • LOC100349106
  • Cd40
  • CD40
  • Dctn2
Alternatives
anti-Human CD40 antibody for Flow Cytometry
Reactivity
Human
633
315
67
21
15
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11
8
4
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2
1
1
1
1
Host
Mouse
499
214
160
23
4
4
Clonality (Clone)
Monoclonal ()
Conjugate
This CD40 antibody is conjugated to PE
95
91
53
21
21
18
15
13
13
12
12
9
9
9
9
9
9
9
8
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6
4
4
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA
572
235
203
153
105
103
94
63
45
33
19
13
13
9
8
8
6
6
4
3
3
3
3
2
2
2
1
1
1
1
1
1
Options
Supplier
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Immunogen Murine L cells transfectants expressing human CD40.

Type of Immunogen: Cells
Clone BE-1
Isotype IgG1
Specificity CD40 Molecule of about 44 kd.
Purification Gel filtration
Alternative Name CD40 (CD40 Antibody Abstract)
Background Name/Gene ID: CD40
Family: TNF Receptor

Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5
Gene ID 958
UniProt P25942
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis, Inflammation, Cancer
Pathways NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity
Application Notes Approved: ELISA, Flo, Func, IP

Usage: Function: Binding of cross linked BE-1 will partially activate B cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer 50 mM sodium phosphate, pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze. Product is photosensitive and should be protected from light.
Storage 4 °C
Storage Comment Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.
Product cited in: Danen, Sonneveld, Brakebusch, Fassler, Sonnenberg: "The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis." in: The Journal of cell biology, Vol. 159, Issue 6, pp. 1071-86, 2002 (PubMed).

Rhee, Sen, Lu, Wu, Leoni, Rubin, Corr, Carson: "Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas." in: Oncogene, Vol. 21, Issue 43, pp. 6598-605, 2002 (PubMed).

Chen, Mosher: "Formation of sodium dodecyl sulfate-stable fibronectin multimers. Failure to detect products of thiol-disulfide exchange in cyanogen bromide or limited acid digests of stabilized matrix fibronectin." in: The Journal of biological chemistry, Vol. 271, Issue 15, pp. 9084-9, 1996 (PubMed).