CD40 antibody (CD40 Molecule, TNF Receptor Superfamily Member 5)

Details for Product anti-CD40 Antibody No. ABIN610078, Supplier: Log in to see
Antigen
  • AI326936
  • Bp50
  • GP39
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TRAP
  • Tnfrsf5
  • p50
  • CDW40
  • TNFRSF5
  • TNFSF5
  • 2310042E05Rik
  • C130077D06Rik
  • C87049
  • DCTN-50
  • GMP23-48K
  • RBP50
  • CD40 antigen
  • CD40 molecule, TNF receptor superfamily member 5
  • dynactin 2
  • LOC100349106
  • Cd40
  • CD40
  • Dctn2
Alternatives
anti-Human CD40 antibody for Agonist
Reactivity
Human
645
312
69
20
14
10
10
6
4
3
2
2
1
1
1
1
Host
Mouse
506
213
166
23
6
4
Clonality (Clone)
Monoclonal ()
Conjugate
This CD40 antibody is un-conjugated
88
85
51
24
24
21
17
15
14
13
12
9
9
9
9
9
9
9
8
7
7
7
7
6
6
5
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA
579
242
205
156
111
104
100
65
46
33
19
15
13
9
8
6
6
4
3
3
3
3
2
2
1
1
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Immunogen Murine L cells transfectants expressing human CD40.

Type of Immunogen: Cells
Clone BE-1
Isotype IgG1
Specificity CD40 Molecule of about 44 kd.
Purification Protein A purified
Alternative Name CD40 (CD40 Antibody Abstract)
Background Name/Gene ID: CD40
Family: TNF Receptor

Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5
Gene ID 958
UniProt P25942
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis, Inflammation, Cancer
Pathways NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Application Notes Approved: ELISA, Flo, Func, IP

Usage: Function: Binding of cross linked BE-1 will partially activate B cells. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride
Preservative Azide free
Handling Advice Do not freeze. Open under aseptic conditions.
Storage 4 °C
Storage Comment Store at +4°C. Do not freeze. Open under aseptic conditions.
Product cited in: Danen, Sonneveld, Brakebusch, Fassler, Sonnenberg: "The fibronectin-binding integrins alpha5beta1 and alphavbeta3 differentially modulate RhoA-GTP loading, organization of cell matrix adhesions, and fibronectin fibrillogenesis." in: The Journal of cell biology, Vol. 159, Issue 6, pp. 1071-86, 2002 (PubMed).

Rhee, Sen, Lu, Wu, Leoni, Rubin, Corr, Carson: "Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas." in: Oncogene, Vol. 21, Issue 43, pp. 6598-605, 2002 (PubMed).

Chen, Mosher: "Formation of sodium dodecyl sulfate-stable fibronectin multimers. Failure to detect products of thiol-disulfide exchange in cyanogen bromide or limited acid digests of stabilized matrix fibronectin." in: The Journal of biological chemistry, Vol. 271, Issue 15, pp. 9084-9, 1996 (PubMed).