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CD46 Molecule, Complement Regulatory Protein (CD46) antibody (PE)

Details for Product No. ABIN610111, Supplier: Log in to see
Antigen
  • AFCP
  • MCP
  • Mcp
  • AHUS2
  • MIC10
  • TLX
  • TRA2.10
  • capping protein (actin filament), gelsolin-like
  • CD46 antigen, complement regulatory protein
  • CD46 molecule, complement regulatory protein
  • Membrane cofactor protein-like
  • CAPG
  • Cd46
  • CD46
  • LOC100341359
Alternatives
anti-Human CD46 Molecule, Complement Regulatory Protein antibody for Flow Cytometry
Reactivity
Human
299
43
42
13
12
5
Host
Mouse
253
99
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
PE
39
27
22
14
12
8
6
6
6
5
5
4
4
4
4
4
4
3
3
3
3
3
2
2
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Western Blotting (WB)
222
213
109
73
64
57
46
27
23
14
7
6
4
3
3
1
Options
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Immunogen Human PBL and EBV transformed LCL.
Clone 169-1-EA-3
Isotype IgG2a
Specificity SCR1 epitope of CD46.
Purification Gel filtration
Alternative Name MCP / CD46 (CD46 Antibody Abstract)
Background Name/Gene ID: CD46

Synonyms: CD46, AHUS2, CD46 antigen, MCP, Measles virus receptor, TLX, MIC10, TRA2.10, Membrane cofactor protein
Gene ID 4179
UniProt P15529
Pathways Regulation of Actin Filament Polymerization
Application Notes Approved: Flo, Func, WB

Usage: Function: Does not block MCP function. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer 50 mM sodium phosphate, pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze. Product is photosensitive and should be protected from light.
Storage 4 °C
Storage Comment Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.
Product cited in: Saucier, Papavasiliou, Palazzo, Naujokas, Kremer, Park: "Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis." in: Oncogene, Vol. 21, Issue 12, pp. 1800-11, 2002 (PubMed).

Elowe, Holland, Kulkarni, Pawson: "Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction." in: Molecular and cellular biology, Vol. 21, Issue 21, pp. 7429-41, 2001 (PubMed).

Miki, Miura, Matuoka, Nakata, Hirokawa, Orita, Kaibuchi, Takai, Takenawa: "Association of Ash/Grb-2 with dynamin through the Src homology 3 domain." in: The Journal of biological chemistry, Vol. 269, Issue 8, pp. 5489-92, 1994 (PubMed).