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ITGA4 antibody (PE)

ITGA4 Reactivity: Human FACS, IHC, Func Host: Mouse Monoclonal BU49 PE
Catalog No. ABIN610121
  • Target See all ITGA4 Antibodies
    ITGA4 (Integrin alpha 4 (ITGA4))
    Reactivity
    • 133
    • 91
    • 35
    • 19
    • 13
    • 9
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 80
    • 49
    • 35
    Mouse
    Clonality
    • 96
    • 70
    • 1
    Monoclonal
    Conjugate
    • 78
    • 16
    • 13
    • 11
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGA4 antibody is conjugated to PE
    Application
    • 99
    • 59
    • 39
    • 32
    • 27
    • 22
    • 13
    • 10
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)
    Specificity
    CD49d molecule of about 145 kd.
    Purification
    Gel filtration
    Immunogen
    Human peripheral myeloma cells.

    Type of Immunogen: Cells
    Clone
    BU49
    Isotype
    IgG1
    Top Product
    Discover our top product ITGA4 Primary Antibody
  • Application Notes
    Approved: Flo, Func, IHC

    Usage: Function: Blocks VLA-4 binding to VCAM-1. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze. Product is photosensitive and should be protected from light.
    Storage
    4 °C
    Storage Comment
    Store at 4°C. Do not freeze. Protect from light.
  • Aplin, Stewart, Assoian, Juliano: "Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1." in: The Journal of cell biology, Vol. 153, Issue 2, pp. 273-82, (2001) (PubMed).

    Short, Boyer, Juliano: "Integrins regulate the linkage between upstream and downstream events in G protein-coupled receptor signaling to mitogen-activated protein kinase." in: The Journal of biological chemistry, Vol. 275, Issue 17, pp. 12970-7, (2000) (PubMed).

  • Target
    ITGA4 (Integrin alpha 4 (ITGA4))
    Alternative Name
    ITGA4 / VLA-4 / CD49d (ITGA4 Products)
    Synonyms
    CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody
    Background
    Name/Gene ID: ITGA4
    Family: Integrin

    Synonyms: ITGA4, 269C wild type, CD49D, IA4, Integrin alpha-4, Integrin alpha 4, Integrin alpha-4 subunit, Integrin alpha-IV, VLA-4, VLA-4 subunit alpha, CD49d antigen
    Gene ID
    3676
    UniProt
    P13612
    Pathways
    Integrin Complex
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