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ITGA4 antibody

ITGA4 Reactivity: Human FACS, IHC, Func Host: Mouse Monoclonal BU49 unconjugated
Catalog No. ABIN610122
  • Target See all ITGA4 Antibodies
    ITGA4 (Integrin alpha 4 (ITGA4))
    Reactivity
    • 135
    • 91
    • 35
    • 19
    • 13
    • 9
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 81
    • 50
    • 35
    Mouse
    Clonality
    • 98
    • 70
    • 1
    Monoclonal
    Conjugate
    • 79
    • 16
    • 14
    • 11
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGA4 antibody is un-conjugated
    Application
    • 100
    • 60
    • 39
    • 34
    • 28
    • 22
    • 13
    • 11
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)
    Specificity
    CD49d molecule of about 145 kd.
    Purification
    Protein A purified
    Immunogen
    Human peripheral myeloma cells.

    Type of Immunogen: Cells
    Clone
    BU49
    Isotype
    IgG1
    Top Product
    Discover our top product ITGA4 Primary Antibody
  • Application Notes
    Approved: Flo, Func, IHC

    Usage: Function: Blocks VLA-4 binding to VCAM-1. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride
    Preservative
    Azide free
    Handling Advice
    Do not freeze. Open under aseptic conditions.
    Storage
    4 °C
    Storage Comment
    Store at 4°C. Do not freeze. Open under aseptic conditions.
  • Aplin, Stewart, Assoian, Juliano: "Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1." in: The Journal of cell biology, Vol. 153, Issue 2, pp. 273-82, (2001) (PubMed).

    Short, Boyer, Juliano: "Integrins regulate the linkage between upstream and downstream events in G protein-coupled receptor signaling to mitogen-activated protein kinase." in: The Journal of biological chemistry, Vol. 275, Issue 17, pp. 12970-7, (2000) (PubMed).

  • Target
    ITGA4 (Integrin alpha 4 (ITGA4))
    Alternative Name
    ITGA4 / VLA-4 / CD49d (ITGA4 Products)
    Synonyms
    CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody
    Background
    Name/Gene ID: ITGA4
    Family: Integrin

    Synonyms: ITGA4, 269C wild type, CD49D, IA4, Integrin alpha-4, Integrin alpha 4, Integrin alpha-4 subunit, Integrin alpha-IV, VLA-4, VLA-4 subunit alpha, CD49d antigen
    Gene ID
    3676
    UniProt
    P13612
    Pathways
    Integrin Complex
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