You are viewing an incomplete version of our website. Please click to reload the website as full version.

Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) antibody

Details for Product No. ABIN610122, Supplier: Log in to see
Antigen
  • LOC100219853
  • CD49D
  • IA4
  • integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
  • integrin alpha 4
  • integrin, alpha 4
  • LOC100219853
  • Itga4
  • ITGA4
Reactivity
Human
269
226
83
15
10
10
9
9
8
7
7
5
4
4
3
2
2
2
2
2
1
1
Host
Mouse
195
184
70
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
78
64
31
8
6
4
4
4
2
2
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (IHC)
358
126
88
73
49
31
31
26
22
18
8
6
4
4
3
3
3
2
2
2
2
2
2
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Immunogen Human peripheral myeloma cells.

Type of Immunogen: Cells
Clone BU49
Isotype IgG1
Specificity CD49d molecule of about 145 kd.
Purification Protein A purified
Alternative Name ITGA4 / VLA-4 / CD49d (ITGA4 Antibody Abstract)
Background Name/Gene ID: ITGA4
Family: Integrin

Synonyms: ITGA4, 269C wild type, CD49D, IA4, Integrin alpha-4, Integrin alpha 4, Integrin alpha-4 subunit, Integrin alpha-IV, VLA-4, VLA-4 subunit alpha, CD49d antigen
Gene ID 3676
UniProt P13612
Application Notes Approved: Flo, Func, IHC

Usage: Function: Blocks VLA-4 binding to VCAM-1. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride
Preservative Azide free
Handling Advice Do not freeze. Open under aseptic conditions.
Storage 4 °C
Storage Comment Store at +4°C. Do not freeze. Open under aseptic conditions.
Product cited in: Aplin, Stewart, Assoian, Juliano: "Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1." in: The Journal of cell biology, Vol. 153, Issue 2, pp. 273-82, 2001 (PubMed).

Short, Boyer, Juliano: "Integrins regulate the linkage between upstream and downstream events in G protein-coupled receptor signaling to mitogen-activated protein kinase." in: The Journal of biological chemistry, Vol. 275, Issue 17, pp. 12970-7, 2000 (PubMed).