FCGR1A antibody (PE)

Catalog No. ABIN610182

Product Details anti-FCGR1A Antibody (PE)

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCGR1A antibody is conjugated to PE

Application: Flow Cytometry (FACS), Western Blotting (WB), Functional Studies (Func)

Specificity: CD64 Molecule of 72 kd from gene Fc gamma RIA.

Purification: Gel filtration

Immunogen: Human rheumatoid synovial fluid cells/monocytes.

Type of Immunogen: Cells

Clone: 10-1

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func, WB

Usage: Function: Blocks binding of Fc gamma RI to immunoglobulin opsonized cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

References for anti-FCGR1A antibody (PE) (ABIN610182)

Weng, Xin, Pablo, Grueneberg, Hagel, Bain, Müller, Papkoff: "Protection against anoikis and down-regulation of cadherin expression by a regulatable beta-catenin protein." in: The Journal of biological chemistry, Vol. 277, Issue 21, pp. 18677-86, (2002) (PubMed).

Jaksits, Kriehuber, Charbonnier, Rappersberger, Stingl, Maurer: "CD34+ cell-derived CD14+ precursor cells develop into Langerhans cells in a TGF-beta 1-dependent manner." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 9, pp. 4869-77, (1999) (PubMed).

Target Details for FCGR1A

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Alternative Name: FCGR1A / CD64 (FCGR1A Products)

Synonyms: CD64 antibody, CD64A antibody, FCRI antibody, IGFR1 antibody, FcgammaRI antibody, Fcgr1 antibody, Fcgr1b antibody, AI323638 antibody, AV092959 antibody, IGGHAFC antibody, FCGR1A antibody, Fc fragment of IgG receptor Ia antibody, Fc receptor, IgG, high affinity I antibody, FCGR1A antibody, Fcgr1a antibody, Fcgr1 antibody

Background: Name/Gene ID: FCGR1A

Synonyms: FCGR1A, CD64A, CD64, CD64 antigen, FCG1, FcgammaRIa, IGFR1, IgG Fc receptor I, Fc-gamma receptor I A1, Fc-gamma RIA, FCGR1, Fc gamma receptor, Fc-gamma RI, FCRI

Gene ID: 2209

UniProt: P12314

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process