FCGR1A antibody

Catalog No. ABIN610183

Product Details anti-FCGR1A Antibody

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Fragment: F(ab')2 fragment

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCGR1A antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Functional Studies (Func)

Specificity: CD64 Molecule of 72 kd from gene Fc gamma RIA.

Purification: Protein A purified

Immunogen: Human rheumatoid synovial fluid cells/monocytes.

Type of Immunogen: Cells

Clone: 10-1

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func, WB

Usage: Function: Blocks binding of Fc gamma RI to immunoglobulin opsonized cells. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

References for anti-FCGR1A antibody (ABIN610183)

Natsugoe, Nakashima, Matsumoto, Xiangming, Okumura, Kijima, Ishigami, Takebayashi, Baba, Takao, Aikou: "Expression of p21WAF1/Cip1 in the p53-dependent pathway is related to prognosis in patients with advanced esophageal carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 5, Issue 9, pp. 2445-9, (1999) (PubMed).

Hurd, Khattree, Alban, Nag, Jhanwar, Dinda, Moudgil: "Hormonal regulation of the p53 tumor suppressor protein in T47D human breast carcinoma cell line." in: The Journal of biological chemistry, Vol. 270, Issue 48, pp. 28507-10, (1996) (PubMed).

Target Details for FCGR1A

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Alternative Name: FCGR1A / CD64 (FCGR1A Products)

Synonyms: CD64 antibody, CD64A antibody, FCRI antibody, IGFR1 antibody, FcgammaRI antibody, Fcgr1 antibody, Fcgr1b antibody, AI323638 antibody, AV092959 antibody, IGGHAFC antibody, FCGR1A antibody, Fc fragment of IgG receptor Ia antibody, Fc receptor, IgG, high affinity I antibody, FCGR1A antibody, Fcgr1a antibody, Fcgr1 antibody

Background: Name/Gene ID: FCGR1A

Synonyms: FCGR1A, CD64A, CD64, CD64 antigen, FCG1, FcgammaRIa, IGFR1, IgG Fc receptor I, Fc-gamma receptor I A1, Fc-gamma RIA, FCGR1, Fc gamma receptor, Fc-gamma RI, FCRI

Gene ID: 2209

UniProt: P12314

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process