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CD70 antibody (CD70 Molecule)

Details for Product anti-CD70 Antibody No. ABIN610194, Supplier: Log in to see
Antigen
  • CD27LG
  • Cd27l
  • Tnfsf7
  • CD27L
  • TNFSF7
  • CD70 antigen
  • CD70 molecule
  • Cd70 molecule
  • Cd70
  • CD70
Reactivity
Human
133
48
5
2
1
1
1
1
1
Host
Mouse
76
59
30
5
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CD70 antibody is un-conjugated
18
17
16
4
2
2
2
1
1
Application
Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), ELISA
81
69
49
47
24
18
18
15
14
10
5
4
4
3
2
2
1
1
1
Options
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Immunogen Human WM-1 (Waldenstrpm's macroglobulinemia) cell line.
Clone BU69
Isotype IgG1
Specificity CD70 Molecule of approximately 30 kd.
Purification Protein A purified
Alternative Name CD70 (CD70 Antibody Abstract)
Background Name/Gene ID: CD70
Family: TNF

Synonyms: CD70, CD27LG, Ki-24 antigen, Surface antigen CD70, CD27 ligand, CD27-L, CD70 antigen, CD70 Molecule, TNFSF7
Gene ID 970
UniProt P32970
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Approved: ELISA, Flo, Func, ICC, IHC-Fr

Usage: Function: Blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.
Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/mL Gentamicin sulfate
Preservative Gentamicin sulfate
Precaution of Use This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at +4°C. DO NOT FREEZE.
Product cited in: Baki, Marambaud, Efthimiopoulos, Georgakopoulos, Wen, Cui, Shioi, Koo, Ozawa, Friedrich, Robakis: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, 2001 (PubMed).

Huan, van Adelsberg: "Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins." in: The Journal of clinical investigation, Vol. 104, Issue 10, pp. 1459-68, 1999 (PubMed).

Background publications Hirano, Kimoto, Shimoyama, Hirohashi, Takeichi: "Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization." in: Cell, Vol. 70, Issue 2, pp. 293-301, 1992 (PubMed).