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p53 antibody (Tumor Protein P53) (PE)

Details for Product anti-TP53 Antibody No. ABIN610212, Supplier: Log in to see
Antigen
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
Alternatives
anti-Mouse (Murine) p53 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Reactivity
Mouse (Murine)
1760
319
271
99
34
18
14
11
11
10
10
9
5
4
4
4
3
3
3
2
2
2
1
Host
Mouse
1238
607
7
4
3
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This p53 antibody is conjugated to PE
54
46
31
27
20
20
17
15
15
14
14
14
14
14
14
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
1371
577
524
318
314
304
234
160
98
84
53
39
35
17
16
12
11
11
11
9
4
3
3
3
2
2
2
1
1
1
1
1
Supplier
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Immunogen Murine p53 fragment expressed in E. coli.
Clone PAb240
Isotype IgG1, kappa
Specificity Denaturization resistant p53 epitope between amino acids 156-214. It is cross reactive with human, mouse, hamster, rat, bovine and chicken tissues.
Cross-Reactivity Chicken, Hamster, Human, Cow (Bovine), Rat (Rattus)
Purification Size Exclusion Chromatography
Alternative Name TP53 / p53 (TP53 Antibody Abstract)
Background Standard Gene Symbol: TP53, Gene Family: P53, Synonyms: TP53, BCC7, Cellular tumor antigen p53, p53, TRP53, p53 tumor suppressor, Phosphoprotein p53, Antigen NY-CO-13, Tumor protein p53, Tumor suppressor p53, LFS1
Gene ID 7157
UniProt P04637
Pathways p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling
Application Notes Flo, IHC, WB
Restrictions For Research Use only
Format Liquid
Buffer 50 mM sodium phosphate, pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15% Glycerol, 0.2% BSA, 0.04% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze. Product is photosensitive and should be protected from light.
Storage 4 °C
Storage Comment Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.
Product cited in: Tomicic, Thust, Kaina: "Ganciclovir-induced apoptosis in HSV-1 thymidine kinase expressing cells: critical role of DNA breaks, Bcl-2 decline and caspase-9 activation." in: Oncogene, Vol. 21, Issue 14, pp. 2141-53, 2002 (PubMed).

Jiang, Clark: "Involvement of Bik, a proapoptotic member of the Bcl-2 family, in surface IgM-mediated B cell apoptosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 10, pp. 6025-33, 2001 (PubMed).

Background publications Boise, González-García, Postema et al.: "bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death." in: Cell, Vol. 74, Issue 4, pp. 597-608, 1993 (PubMed).