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Endoglin (ENG) antibody (PE)

Details for Product No. ABIN610352, Supplier: Log in to see
Antigen
  • ENG
  • MGC137842
  • DKFZp469D0419
  • END
  • HHT1
  • ORW1
  • AI528660
  • AI662476
  • CD105
  • S-endoglin
  • endoglin
  • ENG
  • LOC100226246
  • Eng
Reactivity
Human
554
222
81
34
14
9
5
5
5
3
1
1
1
Host
Mouse
373
220
107
5
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
PE
63
60
47
21
18
15
11
11
11
11
10
7
7
7
7
6
6
6
6
6
6
5
4
4
4
3
2
2
2
2
2
2
2
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), Immunohistochemistry (IHC)
472
424
173
150
111
97
95
80
75
15
14
13
12
7
7
7
6
6
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
Options
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Immunogen Membrane preparation of human B-lineage leukemia cells.
Clone SN6-N1-3A1
Isotype IgG1, kappa
Specificity CD105 homodimer with a molecular weight of about 160 kd.
Purification Gel filtration
Alternative Name CD105 (ENG Antibody Abstract)
Background Name/Gene ID: ENG

Synonyms: ENG, CD105, CD105 antigen, END, HHT1, ORW, ORW1, Osler-Rendu-Weber syndrome 1, Endoglin
Gene ID 2022
UniProt P17813
Research Area Stem Cells, CD Antigens, Surface Receptors of Immune Cells
Application Notes Approved: Flo, Func, IHC

Usage: Function: Augments binding of TGF-b1 to CD105 expressing leukemia cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer 50 mM sodium phosphate, pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze. Product is photosensitive and should be protected from light.
Storage 4 °C
Storage Comment Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.
Product cited in: Taupin, Tian, Kedersha, Robertson, Anderson: "The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1629-33, 1995 (PubMed).

Kawakami, Tian, Duan, Streuli, Schlossman, Anderson: "Identification and functional characterization of a TIA-1-related nucleolysin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8681-5, 1992 (PubMed).