IL7R antibody (Extracellular)

Catalog No. ABIN610367

Product Details anti-IL7R Antibody

Target: IL7R (Interleukin 7 Receptor (IL7R))

Binding Specificity: Extracellular

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Extracellular epitope of recombinant and native CD127 in FACS and Enzyme Immunoassay.

Purification: Protein A purified

Immunogen: Recombinant human CD127.

Type of Immunogen: Recombinant protein

Clone: ANC8F2

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/mL Gentamicin sulfate

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-IL7R antibody (ABIN610367)

Hasegawa, Zinsser, Rhee, Vik-Mo, Davanger, Hay: "Mammalian ykt6 is a neuronal SNARE targeted to a specialized compartment by its profilin-like amino terminal domain." in: Molecular biology of the cell, Vol. 14, Issue 2, pp. 698-720, (2003) (PubMed).

Martinez-Arca, Alberts, Zahraoui, Louvard, Galli: "Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth." in: The Journal of cell biology, Vol. 149, Issue 4, pp. 889-900, (2000) (PubMed).

Chapman, An, Barton, Jahn: "SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils." in: The Journal of biological chemistry, Vol. 269, Issue 44, pp. 27427-32, (1994) (PubMed).

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: IL7R / CD127 (IL7R Products)

Background: Name/Gene ID: IL7R
Family: Interleukin

Synonyms: IL7R, CD127, CD127 antigen, IL-7RA, IL-7 receptor subunit alpha, IL7RA, ILRA, Interleukin 7 receptor, CDW127, IL-7R subunit alpha, IL-7R-alpha

Gene ID: 3575

UniProt: P16871

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size