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CTLA4 antibody (Cytotoxic T-Lymphocyte-Associated Protein 4)

Details for Product anti-CTLA4 Antibody No. ABIN610404, Supplier: Log in to see
Antigen
  • CTLA-4
  • CTLA4
  • CD152
  • Cd152
  • Ctla-4
  • Ly-56
  • CD
  • CELIAC3
  • GRD4
  • GSE
  • IDDM12
  • sCTLA4
Reactivity
Human
180
133
51
7
2
2
Host
Mouse
157
91
78
12
5
4
Clonality (Clone)
Monoclonal ()
Conjugate
This CTLA4 antibody is un-conjugated
53
33
32
15
7
4
3
2
2
2
1
1
1
1
1
1
Application
Functional Studies (Func), Flow Cytometry (FACS), ELISA
219
99
98
57
46
28
20
19
17
7
6
6
5
5
4
4
4
3
2
2
2
1
1
1
1
Supplier
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Immunogen Stimulated human PBL’ s and human CD152 Ig fusion protein.
Clone ANC152-2-8H5
Isotype IgG1, kappa
Specificity CTLA-4 expressed on activated T cells.
Purification Size Exclusion Chromatography
Sterility 0.1 μm filtered
Alternative Name CTLA4 / CD152 (CTLA4 Antibody Abstract)
Background Standard Gene Symbol: CTLA4, Synonyms: CTLA4, CD152, CELIAC3, CD152 antigen, CTLA-4, Celiac disease 3, IDDM12, GRD4, GSE, CD152 isoform
Gene ID 1493
UniProt P16410
Pathways
Application Notes ELISA, Flo, Func
Restrictions For Research Use only
Buffer 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride. Product was 0.1 µm filtered, vialed under aseptic conditions. No preservative added
Handling Advice Do not freeze. Open under aseptic conditions.
Storage 4 °C
Storage Comment Store at +4°C. Do not freeze. Open under aseptic conditions.
Product cited in: Zundel, Swiersz, Giaccia: "Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide." in: Molecular and cellular biology, Vol. 20, Issue 5, pp. 1507-14, 2000 (PubMed).

Chitaev, Troyanovsky: "Adhesive but not lateral E-cadherin complexes require calcium and catenins for their formation." in: The Journal of cell biology, Vol. 142, Issue 3, pp. 837-46, 1998 (PubMed).

Behrens, Vakaet, Friis et al.: "Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC ..." in: The Journal of cell biology, Vol. 120, Issue 3, pp. 757-66, 1993 (PubMed).

Background publications Takeichi: "The cadherins: cell-cell adhesion molecules controlling animal morphogenesis." in: Development (Cambridge, England), Vol. 102, Issue 4, pp. 639-55, 1988 (PubMed).