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PYCARD antibody (PYD and CARD Domain Containing) (AA 121-170)

Details for Product anti-PYCARD Antibody No. ABIN610691, Supplier: Log in to see
Antigen
  • ASC
  • CARD5
  • TMS
  • TMS-1
  • TMS1
  • 9130417A21Rik
  • Asc
  • TNS1
  • masc
  • asc1
  • zAsc
  • zgc:109874
  • PYD and CARD domain containing
  • PYCARD
  • Pycard
  • pycard
Alternatives
anti-Human PYCARD antibody for Western Blotting
Epitope
AA 121-170
38
16
15
13
12
8
7
4
3
3
3
3
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
141
43
27
1
1
1
1
1
Host
Rabbit
99
33
17
Clonality
Polyclonal
Conjugate
This PYCARD antibody is un-conjugated
6
6
5
5
4
4
2
2
2
2
2
2
2
2
1
Application
Western Blotting (WB)
125
60
54
50
36
35
11
5
5
2
2
1
Options
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Immunogen Synthetic peptide located between aa121-170 of human PYCARD (Q9ULZ3, NP_037390). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon (100%), Marmoset (92%), Hamster, Panda, Bat, Rabbit, Horse, Pig (85%), Rat (78%).

Type of Immunogen: Synthetic peptide
Specificity Human PYCARD
Predicted Reactivity Percent identity by BLAST analysis:
Purification Immunoaffinity purified
Alternative Name PYCARD / ASC (PYCARD Antibody Abstract)
Background Name/Gene ID: PYCARD
Family: Apoptosis

Synonyms: PYCARD, CARD5, HASC, ASC, TMS, TMS-1, PYD and CARD domain containing, TMS1
Gene ID 29108
NCBI Accession NP_037390
UniProt Q9ULZ3
Pathways Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization
Application Notes Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Concentration Lot specific
Buffer Lyophilized from PBS with 2 % sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Supplier Images
 image for anti-PYCARD antibody (PYD and CARD Domain Containing) (AA 121-170) (ABIN610691) anti-PYD and CARD Domain Containing (PYCARD) (AA 121-170) antibody
Product cited in: Nakashio, Fujita, Rokudai, Sato, Tsuruo: "Prevention of phosphatidylinositol 3'-kinase-Akt survival signaling pathway during topotecan-induced apoptosis." in: Cancer research, Vol. 60, Issue 18, pp. 5303-9, 2000 (PubMed).

Auphan, DiDonato, Rosette, Helmberg, Karin: "Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis." in: Science (New York, N.Y.), Vol. 270, Issue 5234, pp. 286-90, 1995 (PubMed).

Cordle, Donald, Read, Hawiger: "Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells." in: The Journal of biological chemistry, Vol. 268, Issue 16, pp. 11803-10, 1993 (PubMed).

Haskill, Beg, Tompkins, Morris, Yurochko, Sampson-Johannes, Mondal, Ralph, Baldwin: "Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity." in: Cell, Vol. 65, Issue 7, pp. 1281-9, 1991 (PubMed).