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Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) (C-Term) antibody

Details for Product No. ABIN610759, Supplier: Log in to see
Antigen
  • AI114908
  • ATIII
  • At-3
  • At3
  • AT3
  • AT3D
  • THPH7
  • ANTITHROMBIN, AT-III
  • AT-III
  • serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
  • serpin peptidase inhibitor, clade C (antithrombin), member 1
  • Serpinc1
  • SERPINC1
Epitope
C-Term
11
8
7
7
6
5
5
5
3
3
3
2
2
1
1
1
1
1
1
Reactivity
Dog (Canine), Horse (Equine), Human, Monkey, Mouse (Murine)
226
77
55
8
7
5
5
4
2
1
1
1
1
Host
Rabbit
124
82
34
32
1
1
Clonality
Polyclonal
Conjugate
Un-conjugated
25
16
15
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
132
132
62
39
14
13
10
9
8
8
8
7
7
7
7
3
2
2
1
1
1
Options
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Immunogen Synthetic peptide from C-Terminus of mouse Serpinc1 (P32261, NP_543120). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Elephant, Dog, Horse, Opossum (100%), Rat, Sheep, Panda, Bovine, Bat, Rabbit, Pig, Guinea pig, Platypus (92%), Xenopus (84%), Turkey (83%).

Type of Immunogen: Synthetic peptide
Specificity Mouse SERPINC1 / Antithrombin-III
Predicted Reactivity Percent identity by BLAST analysis: Human, Mouse, Dog, Horse (100%) Rat, Bovine, Rabbit, Pig, Guinea pig (92%).
Purification Immunoaffinity purified
Alternative Name SERPINC1 / Antithrombin III (SERPINC1 Antibody Abstract)
Background Name/Gene ID: SERPINC1

Synonyms: SERPINC1, Antithrombin III, Antithrombin-III, ATIII, AT3, Serpin C1, AT3D, THPH7
Gene ID 462
NCBI Accession NP_543120
UniProt P01008
Application Notes Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Concentration Lot specific
Buffer Lyophilized from PBS with 2 % sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Supplier Images
 image for anti-Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) (C-Term) antibody (ABIN610759) anti-Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) (C-Term) antibody
Product cited in: Cool, Normant, Shen, Chen, Pannell, Zhang, Loh: "Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice." in: Cell, Vol. 88, Issue 1, pp. 73-83, 1997 (PubMed).

Shen, Loh: "Intracellular misrouting and abnormal secretion of adrenocorticotropin and growth hormone in cpefat mice associated with a carboxypeptidase E mutation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 10, pp. 5314-9, 1997 (PubMed).

Varlamov, Fricker: "The C-terminal region of carboxypeptidase E involved in membrane binding is distinct from the region involved with intracellular routing." in: The Journal of biological chemistry, Vol. 271, Issue 11, pp. 6077-83, 1996 (PubMed).

Manser, Fernandez, Loo, Goh, Monfries, Hall, Lim: "Human carboxypeptidase E. Isolation and characterization of the cDNA, sequence conservation, expression and processing in vitro." in: The Biochemical journal, Vol. 267, Issue 2, pp. 517-25, 1990 (PubMed).