ABCC2 antibody (AA 651-700)

Catalog No. ABIN6746219

Product Details anti-ABCC2 Antibody

Target: ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))

Binding Specificity: AA 651-700

Reactivity: Human, Mouse, Rabbit, Cow, Dog, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCC2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Mouse ABCC2 / MRP2

Predicted Reactivity: Percent identity by BLAST analysis: Horse (92%) Mouse, Dog (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa651-700 of mouse Abcc2 (Q8VI47, NP_038834). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rabbit (100%), Elephant, Bat, Horse, Guinea pig (92%), Galago, Rat, Panda, Dog (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-ABCC2 antibody (ABIN6746219)

Lee, Stevens, Hsu, Tsai, Lee, Moss, Vaughan: "Expression in human endothelial cells of ADP-ribosylation factors, 20-kDa guanine nucleotide-binding proteins involved in the initiation of vesicular transport." in: Journal of molecular and cellular cardiology, Vol. 28, Issue 9, pp. 1911-20, (1997) (PubMed).

Morinaga, Tsai, Moss, Vaughan: "Isolation of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP ribosylation factor (ARF) 1 and ARF3 that contains a Sec7-like domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 23, pp. 12856-60, (1996) (PubMed).

Cockcroft, Thomas, Fensome, Geny, Cunningham, Gout, Hiles, Totty, Truong, Hsuan: "Phospholipase D: a downstream effector of ARF in granulocytes." in: Science (New York, N.Y.), Vol. 263, Issue 5146, pp. 523-6, (1994) (PubMed).

Moss, Vaughan: "ADP-ribosylation factors, 20,000 M(r) guanine nucleotide-binding protein activators of cholera toxin and components of intracellular vesicular transport systems." in: Cellular signalling, Vol. 5, Issue 4, pp. 367-79, (1993) (PubMed).

Kahn, Gilman: "Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin." in: The Journal of biological chemistry, Vol. 259, Issue 10, pp. 6228-34, (1984) (PubMed).

Target Details for ABCC2

Target: ABCC2 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2))

Alternative Name: ABCC2 / MRP2 (ABCC2 Products)

Synonyms: ABC30 antibody, CMOAT antibody, DJS antibody, MRP2 antibody, cMRP antibody, AI173996 antibody, Abc30 antibody, Cmoat antibody, Mrp2 antibody, ATP binding cassette subfamily C member 2 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 2 antibody, ABCC2 antibody, Abcc2 antibody

Background: Name/Gene ID: ABCC2
Subfamily: ATP-binding cassette - ABCC/MRP
Family: Transporter

Synonyms: ABCC2, ABC30, CMOAT1, CMOAT, DJS, Multidrug resistance protein 2, MRP2, CMRP

Gene ID: 1244

NCBI Accession: NP_038834

UniProt: Q92887

Pathways: Hormone Transport