MAPK12 antibody (Mitogen-Activated Protein Kinase 12) (AA 289-338)

Details for Product anti-MAPK12 Antibody No. ABIN611036, Supplier: Log in to see
Antigen
  • ATMPK12
  • MAPK12
  • T3F17.28
  • mitogen-activated protein kinase 12
  • MGC160082
  • si:dkey-14d8.5
  • erk6
  • etID309866.18
  • mapk12
  • sapk3
  • wu:fa05c12
  • zgc:101695
  • ERK3
  • ERK6
  • P38GAMMA
  • PRKM12
  • SAPK-3
  • SAPK3
  • AW123708
  • Erk6
  • P38gamma
  • Prkm12
  • Sapk3
  • mitogen-activated protein kinase 12
  • mitogen-activated protein kinase 12b
  • mitogen-activated protein kinase 12a
  • MPK12
  • MAPK12
  • mapk12b
  • mapk12a
  • Mapk12
Alternatives
anti-Human MAPK12 antibody for Immunofluorescence (fixed cells)
Epitope
AA 289-338
27
12
10
8
7
6
5
4
4
4
3
2
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
109
49
20
5
4
4
3
3
2
2
1
1
1
1
Host
Rabbit
81
27
3
2
Clonality
Polyclonal
Conjugate
This MAPK12 antibody is un-conjugated
5
5
4
4
4
4
Application
Western Blotting (WB)
107
53
47
17
14
10
9
2
2
1
1
1
Options
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Immunogen Synthetic peptide located between aa289-338 of mouse Mapk12 (O08911, NP_038899). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Elephant, Rabbit, Opossum (100%), Marmoset, Dog, Bat, Horse, Pig, Guinea pig (92%), Galago, Panda (85%).

Type of Immunogen: Synthetic peptide
Specificity Mouse MAPK12 / ERK5
Predicted Reactivity Percent identity by BLAST analysis: Human, Mouse, Rat, Rabbit (100%) Dog, Horse, Pig, Guinea pig (92%).
Purification Immunoaffinity purified
Alternative Name MAPK12 / ERK6 / SAPK3 (MAPK12 Antibody Abstract)
Background Name/Gene ID: MAPK12
Subfamily: MAPK
Family: Protein Kinase

Synonyms: MAPK12, ERK5, ERK6, ERK-6, MAP kinase 12, MAPK 12, MAP kinase p38 gamma, SAPK3, p38-gamma, p38GAMMA, SAPK-3, ERK3, PRKM12
Gene ID 6300
NCBI Accession NP_038899
UniProt P53778
Pathways MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
Application Notes Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Concentration Lot specific
Buffer Lyophilized from PBS with 2 % sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Supplier Images
 image for anti-MAPK12 antibody (Mitogen-Activated Protein Kinase 12) (AA 289-338) (ABIN611036) anti-Mitogen-Activated Protein Kinase 12 (MAPK12) (AA 289-338) antibody
Product cited in: Fulda, Meyer, Debatin: "Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression." in: Oncogene, Vol. 21, Issue 15, pp. 2283-94, 2002 (PubMed).

Li, Chen, Sinogeeva, Gorospe, Wersto, Chrest, Barnes, Liu: "Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells." in: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 49504-10, 2002 (PubMed).

Background publications Liu, Zou, Slaughter, Wang: "DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis." in: Cell, Vol. 89, Issue 2, pp. 175-84, 1997 (PubMed).