Lcor antibody (AA 331-380)

Catalog No. ABIN6746690

Product Details anti-Lcor Antibody

Target: Lcor (Ligand Dependent Nuclear Receptor Corepressor (Lcor))

Binding Specificity: AA 331-380

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig, Bat, Monkey, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lcor antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human LCOR

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Dog, Bovine, Rabbit, Horse, Pig, Chicken (100%) Zebrafish (93%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa331-380 of human LCOR (Q96JN0, NP_115816). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus (100%), Zebrafish (93%), Galago (92%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-Lcor antibody (ABIN6746690)

Davis-Smyth, Duncan, Zheng, Michelotti, Levens: "The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators." in: The Journal of biological chemistry, Vol. 271, Issue 49, pp. 31679-87, (1997) (PubMed).

Duncan, Collins, Tomonaga, Zhang, Levens: "A unique transactivation sequence motif is found in the carboxyl-terminal domain of the single-strand-binding protein FBP." in: Molecular and cellular biology, Vol. 16, Issue 5, pp. 2274-82, (1996) (PubMed).

Duncan, Bazar, Michelotti, Tomonaga, Krutzsch, Avigan, Levens: "A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif." in: Genes & development, Vol. 8, Issue 4, pp. 465-80, (1994) (PubMed).

Target Details for Lcor

Target: Lcor (Ligand Dependent Nuclear Receptor Corepressor (Lcor))

Alternative Name: MLR2 / LCOR (Lcor Products)

Synonyms: 3110023F06Rik antibody, A630025C20Rik antibody, Mlr2 antibody, mKIAA1795 antibody, MLR2 antibody, RGD1311704 antibody, wu:fd05a07 antibody, zgc:158268 antibody, mlr2 antibody, ligand dependent nuclear receptor corepressor antibody, ligand dependent nuclear receptor corepressor S homeolog antibody, Lcor antibody, LCOR antibody, lcor.S antibody, lcor antibody

Background: Name/Gene ID: LCOR

Synonyms: LCOR, KIAA1795, Ligand-dependent corepressor, Mblk1-related protein 2, MLR2

Gene ID: 84458

NCBI Accession: NP_115816

UniProt: Q6ZPI3