ADAM8 antibody (ADAM Metallopeptidase Domain 8) (AA 70-119)

Details for Product anti-ADAM8 Antibody No. ABIN611315, Supplier: Log in to see
Antigen
  • CD156
  • MS2
  • CD156a
  • E430039A18Rik
  • Adam8
  • adam8
  • reprolysin
  • si:zc217g15.7
  • zgc:64059
  • ADAM8
  • RGD1566394
  • ADAM metallopeptidase domain 8
  • a disintegrin and metalloproteinase domain 8
  • a disintegrin and metallopeptidase domain 8
  • tubulin, gamma complex associated protein 2
  • a disintegrin and metalloproteinase domain 8a
  • ADAM8
  • LOC100304737
  • Adam8
  • Tubgcp2
  • adam8a
  • adam8
Alternatives
anti-Human ADAM8 antibody for Immunofluorescence (fixed cells)
Epitope
AA 70-119
16
15
14
13
12
7
6
5
3
3
2
2
1
1
Reactivity
Human, Monkey, Mouse (Murine)
110
22
21
1
1
Host
Rabbit
61
34
19
Clonality
Polyclonal
Conjugate
This ADAM8 antibody is un-conjugated
7
5
4
4
4
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
81
33
17
13
11
9
8
3
2
1
1
Options
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Immunogen Synthetic peptide located between aa70-119 of human ADAM8 (NP_001100). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%), Mouse (78%).

Type of Immunogen: Synthetic peptide
Specificity Human ADAM8
Predicted Reactivity Percent identity by BLAST analysis: Human (100%).
Purification Immunoaffinity purified
Alternative Name ADAM8 (ADAM8 Antibody Abstract)
Background Name/Gene ID: ADAM8
Subfamily: Metallopeptidase M12B
Family: Protease

Synonyms: ADAM8, ADAM metallopeptidase domain 8, Cell surface antigen MS2, ADAM 8, MS2, CD156, CD156a antigen
Gene ID 101
NCBI Accession NP_001100
UniProt P78325
Research Area Proteolysis / Ubiquitin, Metalloprotease, Extracellular Matrix, Apoptosis/Necrosis
Pathways Activation of Innate immune Response, M Phase
Application Notes Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Concentration Lot specific
Buffer Lyophilized from PBS with 2 % sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Supplier Images
 image for anti-ADAM8 antibody (ADAM Metallopeptidase Domain 8) (AA 70-119) (ABIN611315) anti-ADAM Metallopeptidase Domain 8 (ADAM8) (AA 70-119) antibody
Product cited in: Barbara, Wrana, Letarte: "Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 584-94, 1999 (PubMed).

Li, Sorensen, Brooke, Urness, Davis, Taylor, Boak, Wendel: "Defective angiogenesis in mice lacking endoglin." in: Science (New York, N.Y.), Vol. 284, Issue 5419, pp. 1534-7, 1999 (PubMed).

Bellón, Corbí, Lastres, Calés, Cebrián, Vera, Cheifetz, Massague, Letarte, Bernabéu: "Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions." in: European journal of immunology, Vol. 23, Issue 9, pp. 2340-5, 1993 (PubMed).

Gougos, Letarte: "Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells." in: The Journal of biological chemistry, Vol. 265, Issue 15, pp. 8361-4, 1990 (PubMed).