HLA-DMA antibody (AA 58-107)

Catalog No. ABIN6746965

Product Details anti-HLA-DMA Antibody

Target: HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Binding Specificity: AA 58-107

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-DMA antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Human HLA-DMA

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Rabbit (81%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa58-107 of human HLA-DMA (Q31604, NP_006111). Percent identity by BLAST analysis: Human (100%), Marmoset (92%), Hamster (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-HLA-DMA antibody (ABIN6746965)

Nagamine, Kudoh, Kawasaki, Minoshima, Asakawa, Ito, Shimizu: "Genomic organization and complete nucleotide sequence of the TMEM1 gene on human chromosome 21q22.3." in: Biochemical and biophysical research communications, Vol. 235, Issue 1, pp. 185-90, (1997) (PubMed).

Scott, Chen, Rossier, Lalioti, Antonarakis: "Isolation of a human gene (HES1) with homology to an Escherichia coli and a zebrafish protein that maps to chromosome 21q22.3." in: Human genetics, Vol. 99, Issue 5, pp. 616-23, (1997) (PubMed).

Target Details for HLA-DMA

Target: HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))

Alternative Name: HLA-DMA (HLA-DMA Products)

Synonyms: RT1.Ma antibody, RT1.DMa antibody, HLA-DMA antibody, H-2Ma antibody, H2-Ma antibody, D6S222E antibody, DMA antibody, HLADM antibody, RING6 antibody, RT1 class II, locus DMa antibody, SLA-DM alpha chain antibody, major histocompatibility complex, class II, DM alpha antibody, histocompatibility 2, class II, locus DMa antibody, RT1-DMa antibody, SLA-DMA antibody, DLA-DMA antibody, H2-DMa antibody, HLA-DMA antibody

Background: Name/Gene ID: HLA-DMA

Synonyms: HLA-DMA, DMA, RING6, D6S222E, HLADM, MHC class II antigen DMA

Gene ID: 3108

NCBI Accession: NP_006111

UniProt: P28067

Pathways: Cancer Immune Checkpoints