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Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) antibody

Antigen

Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C)
Synonyms Cdc25, CDC25C, CDC25, cdc25, xcdc25c
Clonality Monoclonal (1F12)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
3 references available
Catalog no. ABIN614228
Quantity 0.1ml  (1. 000mg/ml)
Price 546.86 $   Plus shipping costs $45.00
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anti-Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C) antibody

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name CDC25C
Gene ID 995
UniProt Q9UM07
Immunogen Purified recombinant fragment of human CD14 expressed in E. Coli.
Format Liquid
Isotype IgG1
Clone 1F12
Description Synonyms: CDC25, CDC25C.
Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Specificity Rabbit polyclonal to PADI4
Molecular Weight 58kDa

Application Details
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Application Notes WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ELISA: 1/10000
Concentration 1. 000mg/ml
Purity > 90%
Purification Ascitic fluid
Preservative 0.03% sodium azide
Storage Store at 4°C, for long term storage, store at -20°C
Research Area Cell Cycle
Restrictions For Research Use only

Publications
Application Details Images Alternatives back to top

Product Vecchione, Baldassarre, Ishii et al.: "Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development." in: Cancer cell, Vol. 11, Issue 3, pp. 275-89, 2007 (PubMed).

Busch, Barton, Morgenstern et al.: "The G2/M checkpoint phosphatase cdc25C is located within centrosomes." in: The international journal of biochemistry & cell biology, Vol. 39, Issue 9, pp. 1707-13, 2007 (PubMed).

Zheng, Kosti, Loffredo et al.: "Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 9, pp. 2199-210, 2010 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C)", type "Antibodies"
Hosts Rabbit (77), Mouse (30)
Reactivities Human (105), Mouse (Murine) (33), Rat (Rattus) (33), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)
Applications Western Blotting (WB) (70), Immunofluorescence (IF) (49), ELISA (32), Immunohistochemistry (IHC) (23), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (23), Immunoprecipitation (IP) (21), Immunocytochemistry (ICC) (12), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), PE,Cy5.5 (2), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
Epitopes pSer216 (14), pThr48 (6), C-Term (3), N-Term (3), Internal Region (2), Ser216 (2), AA 1-258 (1), Center (1), pSer178 (1), pSer198 (1), pThr161 (1)