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CD9 antibody (CD9) (PE)

Details for Product anti-CD9 Antibody No. ABIN614778, Supplier: Log in to see
Antigen
  • Tspan29
  • BTCC-1
  • DRAP-27
  • MIC3
  • MRP-1
  • TSPAN-29
  • TSPAN29
Reactivity
Mouse (Murine)
330
78
27
25
21
21
21
20
13
8
7
7
7
7
6
6
1
1
Host
Rat
264
76
50
Clonality (Clone)
Monoclonal ()
Conjugate
This CD9 antibody is conjugated to PE
55
52
31
14
5
5
3
2
1
1
1
Application
Flow Cytometry (FACS)
289
174
94
68
56
40
38
37
25
19
5
4
2
2
2
2
2
1
1
1
Supplier
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Immunogen Permeabilized murine bone marrow-derived mast cells (BMMC)
Clone EM-04
Isotype IgG1
Specificity This antibody recognizes CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
Cross-Reactivity (Details) Species reactivity (tested):Mouse
Alternative Name CD9 (CD9 Antibody Abstract)
Background CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.Synonyms: 5H9 antigen, Cell growth-inhibiting gene 2 protein, GIG2, Leukocyte antigen MIC3, MIC3, Motility-related protein, TSPAN29, Tetraspanin-29, p24
Gene ID 12527
NCBI Accession NP_031683
UniProt P40240
Research Area Embryogenesis, Embryonic stem cells, Reproduction, CD Antigens, Surface Receptors of Immune Cells
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE! This product is photosensitive and should be protected from light.
Storage 4 °C
Supplier Images
Western Blotting (WB) image for anti-CD9 antibody (CD9)  (PE) (ABIN614778) anti-CD9 (CD9) antibody (PE)
Background publications Kotha, Zhang, Longhurst et al.: "Functional relevance of tetraspanin CD9 in vascular smooth muscle cell injury phenotypes: a novel target for the prevention of neointimal hyperplasia." in: Atherosclerosis, Vol. 203, Issue 2, pp. 377-86, 2009 (PubMed).

Unternaehrer, Chow, Pypaert et al.: "The tetraspanin CD9 mediates lateral association of MHC class II molecules on the dendritic cell surface." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 1, pp. 234-9, 2007 (PubMed).

Liu, Cao, Yang et al.: "Tetraspanin CD9 regulates invasion during mouse embryo implantation." in: Journal of molecular endocrinology, Vol. 36, Issue 1, pp. 121-30, 2006 (PubMed).

Le Naour, Rubinstein, Jasmin et al.: "Severely reduced female fertility in CD9-deficient mice." in: Science (New York, N.Y.), Vol. 287, Issue 5451, pp. 319-21, 2000 (PubMed).

Schmidt, Künemund, Wintergerst et al.: "CD9 of mouse brain is implicated in neurite outgrowth and cell migration in vitro and is associated with the alpha 6/beta 1 integrin and the neural adhesion molecule L1." in: Journal of neuroscience research, Vol. 43, Issue 1, pp. 12-31, 1996 (PubMed).